Managing Recurring Genital Warts: Treatment Options and Concerns - Urology

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The issue of recurrence of cauliflower (condylomata acuminata)?


Hello doctor, my onset of symptoms was at the end of September 2016 when I was diagnosed with genital warts located near the vaginal opening and labia.
I underwent electrosurgery on October 8.
After the procedure, I applied a topical ointment prescribed by my gynecologist to aid in wound healing.
Once the wound healed, I used a box of Aldara (imiquimod) and returned for follow-up appointments weekly.
Initially, I saw improvement, but after a week, the warts recurred in a different location, now near the vaginal and anal openings, prompting me to seek further treatment.

I later underwent a biopsy to confirm the presence of genital warts, and after confirmation, the doctor recommended pausing electrosurgery and switching to topical treatment with a wart remover, which I also applied weekly.
The initial application was quite painful, but the doctor mentioned that recovery was progressing quickly.
Subsequently, I was prescribed another package of Aldara for healing.
However, during my next follow-up, I noticed another recurrence in a different location, with new growths appearing near the anal area and labia, some small and some larger.
The doctor indicated that the larger ones did not appear to be genital warts and suggested further examination.
I was supposed to undergo a biopsy but opted out due to the pain, so I did not get checked.
I would like to ask how long this recurring issue might continue, as the growths keep appearing in different spots, which is quite distressing.
Is there a possibility of combining oral medication with topical treatment for a more effective approach?

Ning, 20~29 year old female. Ask Date: 2017/01/29

Dr. Du Shixi reply Urology


Hello: If you have been seen at a clinic, I recommend that you go to a hospital.
Some warts can be treated and may not cause further issues, while others can recur frequently and are very difficult to heal (this is related to the strength of the virus and your immune system).
Additionally, your sexual partner should be checked.
If you do not have a stable partner and do not engage in safe sex, it is advisable to have other sexually transmitted infections checked at the hospital.
Right now, you need to strengthen your immune system by ensuring adequate sleep, exercising a little each day, avoiding spicy foods and alcohol, and consuming fruits.
Thank you for your inquiry.
Currently, sexual activity is not recommended because the location of your lesions is difficult to protect (also, any suspected lesions should be confirmed pathologically).

Reply Date: 2017/01/29

More Info


Managing recurring genital warts can be quite challenging, especially when they keep reappearing in different locations. Genital warts, caused by certain strains of the human papillomavirus (HPV), can be persistent and may require a multifaceted approach to treatment. Here’s a comprehensive overview of treatment options, concerns, and management strategies.


Treatment Options
1. Topical Treatments:
- Imiquimod (Aldara): This is an immune response modifier that helps your body fight the HPV infection. It is applied directly to the warts and can be effective in reducing their size and number.

- Podophyllin and Podofilox: These are plant-derived compounds that destroy wart tissue. They are typically applied by a healthcare provider, but Podofilox can also be used at home.

- Trichloroacetic Acid (TCA): This is a chemical treatment that can be applied to the warts by a healthcare provider. It works by destroying the wart tissue.

2. Surgical Options:
- Electrosurgery: This method uses electrical currents to burn off warts. It is effective but may require multiple sessions.

- Cryotherapy: Freezing the warts with liquid nitrogen is another option. This can be painful and may also require several treatments.

- Laser Therapy: This is typically reserved for larger or more stubborn warts and can be effective but is usually more costly.

3. Oral Medications:
- While there are no specific oral medications approved for the treatment of genital warts, some antiviral medications may be prescribed in certain cases, especially if there is a significant recurrence or if the warts are extensive. However, these are not standard treatments for genital warts.


Concerns and Considerations
- Recurrence: It’s common for genital warts to recur after treatment. This is because the HPV virus can remain dormant in the body. Even after the visible warts are treated, the virus can still be present and may cause new warts to develop.

- Different Locations: The appearance of warts in different locations can be frustrating. It’s essential to have regular follow-ups with your healthcare provider to monitor and manage these changes effectively.

- Pain and Discomfort: Treatments like cryotherapy and electrosurgery can be painful. Discuss pain management options with your healthcare provider to make the process more tolerable.

- Psychological Impact: The recurring nature of genital warts can lead to anxiety and stress. It’s important to address these feelings and consider counseling or support groups if needed.


Management Strategies
1. Regular Follow-ups: Consistent follow-up appointments with your healthcare provider are crucial. They can monitor the situation and adjust treatment plans as necessary.

2. Self-Care: Maintain good hygiene and avoid irritants in the genital area. This can help reduce discomfort and prevent further irritation.

3. Healthy Lifestyle: A strong immune system can help your body fight off infections. Eating a balanced diet, exercising regularly, and managing stress can all contribute to better overall health.

4. Communication with Healthcare Provider: If you experience new symptoms or have concerns about the treatments, communicate openly with your healthcare provider. They can provide guidance and possibly recommend alternative treatments.


Conclusion
Managing recurring genital warts requires a comprehensive approach that includes topical treatments, possible surgical interventions, and ongoing monitoring. While there is no definitive cure for HPV, effective management strategies can help control outbreaks and improve your quality of life. If you have concerns about the treatments or the recurrence of warts, discussing these with your healthcare provider is essential to find the best approach for your situation.

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