Prostatitis: When Symptoms Persist Despite Treatment - Urology

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Hello, doctor?


Doctor, I have been taking ciprofloxacin for a month for prostatitis, but there has been no improvement in the discomfort in my perineum.
I previously had a semen culture that showed bacteria, but other doctors have told me that those bacteria might just be contaminants and advised me not to worry or continue taking medication, stating that the inflammation is not severe (indicated by a digital rectal exam showing 2-5 white blood cells in the urine).
They believe my discomfort is due to my anxiety about having an infection (I have felt strange sensations at the urethral opening after sexual activity, but there is no discharge or pain, and the prostate issues arose nearly three weeks later).
They also suggested that it could be due to cycling or lack of sleep, but I do not have those habits.
Should I consider other infections, such as trichomoniasis or mycoplasma, or is it possible that anxiety could cause such a level of discomfort? Thank you for your hard work in answering my questions, doctor.

Hao zhe ji, 20~29 year old female. Ask Date: 2017/02/09

Dr. Du Shixi reply Urology


Hello: Based on your description, I can only say that many people experience similar situations, but it may take some time to improve.
Most tests are usually normal.
If you are diagnosed in a hospital, please return for regular follow-ups, such as every two weeks.
If you are being treated at a clinic, I recommend going to a larger hospital for more confidence in your care.
Currently, if your symptoms change, you should seek medical attention and take medication as prescribed; if there are no symptoms, medication is not necessary.
It's important to pay attention to your lifestyle, such as avoiding alcohol and spicy foods, limiting sugary drinks, and drinking plenty of plain water (ideally, your urine should be light in color).
Avoid sitting or standing for long periods (get up and move around every few hours), and aim for a daily walk of at least half an hour (not just walking to work).
Eat plenty of fruits and vegetables.
If you have multiple sexual partners, practice safe sex, and make sure to urinate after sexual activity (trichomoniasis or mycoplasma are rare).
[Some of my patients experience sudden improvements, but symptoms may reappear after a period of neglect in their lifestyle, just a reminder for you.] Thank you for your inquiry.

Reply Date: 2017/02/09

More Info


Prostatitis, particularly chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), can be a challenging condition to manage, especially when symptoms persist despite treatment. Your experience with ciprofloxacin for a month without improvement in perineal discomfort is not uncommon in cases of non-bacterial prostatitis. It is essential to understand that not all cases of prostatitis are due to bacterial infections, and many patients may experience symptoms without any identifiable pathogens.

In your situation, the fact that other physicians have suggested that the bacteria found in your semen culture might be contaminants is significant. This is a common issue in urology, where the presence of bacteria does not always correlate with an active infection. The low white blood cell count in your urine (2-5) further supports the idea that there may not be a significant inflammatory process occurring.

Chronic pelvic pain can arise from various factors, including psychological stress, anxiety, and lifestyle habits. It is well-documented that anxiety and stress can exacerbate physical symptoms, leading to a cycle of discomfort and worry. In your case, the persistent feeling of discomfort after sexual activity, despite the absence of discharge or pain, could be linked to heightened anxiety about potential infections. This psychological component can manifest physically, leading to muscle tension and discomfort in the pelvic region.

Regarding your concerns about other infections, such as Trichomonas or Mycoplasma, it is essential to consider that these infections typically present with more specific symptoms, such as discharge or pain during urination. If you are not experiencing these symptoms, the likelihood of these infections being the cause of your discomfort is lower. However, if you have concerns, discussing further testing with your healthcare provider may be beneficial.

In terms of management, since you have already tried antibiotics without success, it may be time to explore other treatment modalities. Here are some options that might be considered:
1. Pelvic Floor Physical Therapy: Many patients with CP/CPPS benefit from physical therapy focused on the pelvic floor. This therapy can help alleviate muscle tension and improve pelvic floor function.

2. Pain Management: Non-steroidal anti-inflammatory drugs (NSAIDs) can help manage pain. Additionally, some patients find relief with medications that target nerve pain, such as gabapentin or pregabalin.

3. Lifestyle Modifications: Regular exercise, stress management techniques (such as mindfulness or cognitive-behavioral therapy), and dietary changes can also play a role in symptom management. Avoiding irritants like caffeine, alcohol, and spicy foods may help reduce discomfort.

4. Alternative Therapies: Some patients find relief through acupuncture, biofeedback, or other complementary therapies. While evidence varies, these approaches may provide additional support.

5. Regular Follow-Up: Since prostatitis can be a chronic condition, maintaining regular follow-up with your healthcare provider is crucial. They can monitor your symptoms and adjust your treatment plan as necessary.

In conclusion, while it is understandable to be concerned about persistent symptoms, it is essential to approach this condition holistically. Addressing both the physical and psychological aspects of your symptoms can lead to better outcomes. If you continue to experience discomfort, consider discussing a comprehensive treatment plan with your healthcare provider that includes physical therapy, pain management strategies, and lifestyle modifications. Remember, you are not alone in this journey, and many resources are available to help you manage your symptoms effectively.

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