Managing Seborrheic Dermatitis: Concerns About Medication Side Effects - Dermatology

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Issues with applying medication for seborrheic dermatitis?


Hello Doctor, I visited a dermatologist the day before yesterday who prescribed me a cream for seborrheic dermatitis.
After applying it, the next day around noon, my cheeks and forehead became very red, but the redness subsided before bedtime.
I applied the medication before sleeping, but when I woke up the next day, my cheeks were slightly red.
After washing my face with water, I felt a stinging and burning sensation on my cheeks and forehead, which was quite alarming.
My face seems to be worse now than it was before seeing the doctor.
I am taking Zyrtec and using a cream that contains Betamethasone and Neomycin.
Thank you for your response, Doctor.

Toby, 20~29 year old female. Ask Date: 2017/02/15

Dr. Wu Yuxin reply Dermatology


You should consult your attending physician about this issue, as they are most familiar with your condition and can help you choose the appropriate medication.

Reply Date: 2017/02/15

More Info


Managing seborrheic dermatitis can be challenging, especially when medications lead to unexpected side effects. In your case, it seems that the topical medication prescribed, which contains Betamethasone and Neomycin, has caused increased redness, burning, and stinging sensations on your face. These symptoms can indeed be concerning and may indicate a reaction to the medication.

Understanding the Medications:
1. Betamethasone: This is a potent corticosteroid used to reduce inflammation and treat various skin conditions, including seborrheic dermatitis. While effective, it can lead to side effects such as skin thinning, irritation, and in some cases, worsening of the condition if used excessively or improperly.


2. Neomycin: This is an antibiotic that helps prevent or treat bacterial infections. However, it can also cause allergic reactions in some individuals, leading to symptoms like redness, itching, and rash.

Possible Side Effects:
The symptoms you are experiencing—redness, burning, and stinging—are common side effects associated with both Betamethasone and Neomycin. These reactions can occur due to:
- Allergic Reaction: Some individuals may develop an allergy to Neomycin, leading to contact dermatitis, which manifests as redness and irritation.

- Corticosteroid Rebound Effect: If the corticosteroid is used for an extended period, stopping it suddenly can lead to a rebound effect where the skin condition worsens temporarily.

- Skin Sensitivity: The skin may become more sensitive due to the medication, especially if used on delicate areas like the face.

Duration of Side Effects:
The duration of these side effects can vary. Generally, if the medication is stopped, mild reactions may improve within a few days to a week. However, if the symptoms persist or worsen, it is crucial to consult your healthcare provider for further evaluation.

Management Strategies:
1. Discontinue Use: If you suspect that the medication is causing adverse effects, it may be wise to stop using it. However, this should be done under the guidance of your healthcare provider.


2. Gentle Skin Care: Use a mild, fragrance-free cleanser and avoid harsh scrubs or exfoliants. Moisturizing your skin with a gentle, hydrating lotion can help soothe irritation.

3. Cold Compress: Applying a cold compress to the affected areas can help reduce redness and burning sensations.

4. Antihistamines: If itching is a significant issue, over-the-counter antihistamines like Zyrtec (which you are already taking) may help alleviate some discomfort.

5. Follow-Up: It is essential to follow up with your dermatologist. They may recommend alternative treatments, such as different topical medications or a lower potency corticosteroid, to manage your seborrheic dermatitis without causing adverse effects.

6. Consider Alternative Treatments: Depending on the severity of your condition, your dermatologist might suggest other treatments such as antifungal creams, medicated shampoos, or even systemic medications if necessary.

In conclusion, while Betamethasone and Neomycin can be effective for treating seborrheic dermatitis, they can also lead to side effects that may exacerbate your condition. Monitoring your symptoms and maintaining open communication with your healthcare provider is crucial for effective management. If your symptoms do not improve or worsen, seeking immediate medical advice is essential to ensure proper care and treatment.

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