Overdose of Dexamethasone 54mg?
Hello Doctor: I have been taking medication for attention deficit for four years, and my weight is 48 kg.
Recently, I have been taking 36 mg of Dexedrine for the past three months, but I switched to 54 mg of Dexedrine.
I take one Dexedrine on an empty stomach in the morning before breakfast, about an hour later.
I originally intended to take cold medicine but accidentally took Dexedrine instead.
I would like to know if taking 108 mg of Dexedrine will harm my body (such as the liver, kidneys, or brain).
Should I stop taking the medication for a few days to allow my body to metabolize it?
17, 10~19 year old female. Ask Date: 2017/02/22
Dr. Zhang Fangrong reply Psychiatry
Dear Sir/Madam,
According to current knowledge regarding drug reactions, the peak plasma concentration of the medication is reached 6-8 hours after administration, after which the plasma concentration gradually decreases.
Therefore, theoretically, by the next day, the drug concentration should have decreased to a safe level, especially since you took 108 mg.
If you choose to temporarily discontinue the medication the following day, it should be a sufficiently safe approach.
Possible physical effects may include gastrointestinal symptoms such as vomiting, central nervous system symptoms like agitation, and cardiovascular symptoms such as headaches or tachycardia.
If you experience any significant discomfort, it is advisable to seek medical attention promptly.
However, since 108 mg is not considered a very high dose, I hope it will not cause you any distress.
Thank you for your inquiry, and I wish you mental and physical well-being.
Sincerely,
Dr.
Fang-Rong Chang
General Psychiatry
Reply Date: 2017/02/22
More Info
Concerns about medication dosages, especially for stimulant medications like Concerta (methylphenidate), are valid and should be taken seriously. Concerta is commonly prescribed for Attention Deficit Hyperactivity Disorder (ADHD) and is designed to help improve focus and attention. However, it is crucial to adhere to the prescribed dosage to avoid potential side effects and complications.
Understanding the Dosage
You mentioned that you have been taking Concerta for four years and recently increased your dosage to 54 mg. The maximum recommended dose for Concerta is typically 72 mg per day for adults, depending on individual circumstances and the prescribing physician's guidance. Therefore, a single dose of 54 mg is within the acceptable range, but it is essential to consider how this dosage interacts with your body, especially given your weight of 48 kg (approximately 106 lbs).
Potential Risks of Overdosing
Taking a higher dose than prescribed, such as accidentally consuming 108 mg (if you took an additional dose), can lead to several side effects. These may include:
1. Cardiovascular Issues: Stimulants can increase heart rate and blood pressure. Overdosing may exacerbate these effects, leading to palpitations, increased anxiety, or even more severe cardiovascular events in susceptible individuals.
2. Neurological Effects: High doses can lead to symptoms such as agitation, insomnia, headaches, or even seizures in extreme cases.
3. Gastrointestinal Distress: Nausea, vomiting, or abdominal pain can occur with higher doses.
4. Psychiatric Symptoms: Increased anxiety, mood swings, or even psychosis can occur with stimulant overdoses.
What to Do After an Accidental Overdose
If you suspect that you have taken an overdose of Concerta (108 mg), it is crucial to monitor yourself for any adverse effects. Here are some steps you should consider:
1. Contact a Healthcare Professional: Reach out to your prescribing physician or a healthcare provider immediately. They can provide personalized advice based on your medical history and current health status.
2. Do Not Self-Medicate: Avoid taking any additional medications or trying to counteract the effects without professional guidance.
3. Hydration and Rest: Ensure you stay hydrated and try to rest. Avoid stimulants such as caffeine, which can exacerbate symptoms.
4. Monitor Symptoms: Keep track of any symptoms you experience, such as increased heart rate, anxiety, or gastrointestinal issues, and report these to your healthcare provider.
Metabolism and Recovery
Regarding your question about whether you need to stop taking the medication for a few days to allow your body to metabolize the excess, it largely depends on the severity of any symptoms you may be experiencing. If you feel unwell or have significant side effects, your doctor may recommend a temporary cessation of the medication or an adjustment of your dosage.
Conclusion
In summary, while a single instance of taking a higher dose of Concerta may not lead to severe consequences, it is essential to approach this situation with caution. Always communicate openly with your healthcare provider about any concerns or incidents related to your medication. They can help you navigate any necessary adjustments to your treatment plan and ensure your safety and well-being. Regular follow-ups and open communication with your healthcare team are vital in managing ADHD effectively while minimizing risks associated with medication.
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