the Connection Between Thalassemia and Rapid Heart Rate in Children - Cardiology

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Hello doctor, my child has thalassemia and recently, within the past six months, has frequently experienced a rapid heartbeat of over 120 beats per minute and shortness of breath after exercising at school.
Could this be related to thalassemia?

Xiao Kai, 30~39 year old female. Ask Date: 2017/03/04

Dr. He Dongjin reply Cardiology


Hello, it's hard to say.
It depends on the severity of the anemia, any potential heart issues, or insufficient physical activity and lung capacity.
It is advisable to visit a cardiology clinic for further examination.
Changhua Hospital cares about your well-being.

Reply Date: 2017/03/04

More Info


Thalassemia, particularly the more common form known as beta-thalassemia, is a genetic blood disorder that results in reduced production of hemoglobin. This can lead to anemia, which is characterized by a lower than normal number of red blood cells or hemoglobin in the blood. In children with thalassemia, especially those who are not adequately treated or managed, the body may struggle to deliver sufficient oxygen to tissues during physical activity. This can result in symptoms such as rapid heart rate (tachycardia) and shortness of breath, particularly during exertion.

When a child with thalassemia engages in physical activity, their body requires more oxygen to meet the increased metabolic demands. However, due to the underlying anemia caused by thalassemia, the blood may not be able to transport enough oxygen. As a compensatory mechanism, the heart beats faster to try to deliver more oxygenated blood to the tissues. This can lead to episodes of tachycardia, where the heart rate exceeds 120 beats per minute, as you have observed in your child.

Additionally, children with thalassemia may experience other complications that can exacerbate symptoms during physical activity. For instance, they may have an enlarged spleen or liver, which can affect their overall physical capacity. They may also be more prone to fatigue and weakness due to chronic anemia, which can further limit their ability to engage in strenuous activities without experiencing rapid heart rates and shortness of breath.

It is also important to consider that children with thalassemia may have other associated conditions, such as iron overload due to frequent blood transfusions, which can affect heart function and overall health. Regular monitoring and management of thalassemia, including appropriate blood transfusions, iron chelation therapy, and folic acid supplementation, are crucial to minimize complications and improve quality of life.

In your child's case, it is essential to discuss these symptoms with a healthcare provider who specializes in hematology or pediatric care. They may recommend further evaluation, including blood tests to assess hemoglobin levels, reticulocyte counts, and possibly echocardiography to evaluate heart function. It may also be beneficial to develop a tailored exercise plan that takes into account your child's condition, ensuring that they can participate in physical activities safely without undue strain on their cardiovascular system.

In summary, the rapid heart rate your child experiences after exercise is likely related to their thalassemia and the resulting anemia. It is crucial to work closely with healthcare professionals to manage their condition effectively and to ensure they can engage in physical activities safely. Regular follow-ups and monitoring will help in adjusting treatment plans as needed and in addressing any emerging concerns related to their health and well-being.

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