Immunity: Should You Get Tested After Shingles Recurrence? - Family Medicine

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Immune system assessment?


Hello Doctor: I was diagnosed with shingles six years ago, and it seems to have recurred recently (mildly).
I heard from a doctor that this condition typically does not recur unless there is an abnormality in the immune system.
However, I am only 24 years old and do not often catch colds.
Is it possible that I have an immune system abnormality? I am very concerned and would like to undergo a health check-up.
I would like to know if a routine blood test can assess immune function.
Which department should I visit for what kind of tests? Thank you very much.

Ma Li Ao, 20~29 year old female. Ask Date: 2017/03/07

Dr. Huang Xunying reply Family Medicine


Hello: The virus that causes shingles remains dormant in your nerve roots after healing.
Therefore, whenever your immune system weakens, shingles can recur, and it is also possible for young people to develop shingles.
Additionally, blood tests that are more related to immune function include white blood cell count and white blood cell differential.
If you would like to learn more about related topics, you can consult a family medicine specialist.
Thank you.

Reply Date: 2017/03/07

More Info


Shingles, or herpes zoster, is caused by the reactivation of the varicella-zoster virus, which also causes chickenpox. It is indeed true that shingles typically occurs in individuals with weakened immune systems, but it can also occur in otherwise healthy individuals, particularly if they have experienced significant stress, illness, or other factors that may temporarily lower their immune response.
At 24 years old, it is less common to experience shingles, but it is not impossible. The recurrence of shingles can be concerning, especially if it is happening after a significant period since your initial outbreak. While it is generally believed that shingles does not frequently recur in healthy individuals, there are exceptions. Factors such as stress, fatigue, or other underlying health issues can contribute to a weakened immune system, making it more susceptible to viral reactivation.

If you are worried about your immune system, it is a good idea to consult with a healthcare provider. They can help assess your situation and determine whether further evaluation is necessary.
Regarding your question about blood tests and immune function, standard blood tests can provide some insights into your immune health. For example, a complete blood count (CBC) can show the levels of various types of white blood cells, which are crucial for fighting infections. A low white blood cell count may indicate an underlying issue with your immune system. Additionally, specific tests can measure immunoglobulin levels, which are antibodies that play a vital role in immune response.
If you are looking to evaluate your immune function more comprehensively, you might consider asking your doctor about specific immunological tests. These could include:
1. Immunoglobulin Levels: This test measures the levels of different types of antibodies in your blood (IgG, IgA, IgM, etc.). Abnormal levels can indicate issues with your immune system.

2. Lymphocyte Subset Analysis: This test evaluates the different types of lymphocytes (a type of white blood cell) in your blood, which can help assess your immune response.

3. Vaccine Response Testing: If you have received vaccines, your doctor may check how well your immune system responded to them, which can provide insight into your immune function.

4. Specific Antibody Tests: These tests can check for antibodies against specific pathogens, helping to determine if your immune system is effectively responding to infections.

You should visit a healthcare provider, such as a primary care physician or an immunologist, who can guide you through the appropriate tests based on your symptoms and medical history. They will be able to interpret the results and provide recommendations based on your individual situation.

In summary, while shingles recurrence can be alarming, it does not necessarily indicate a severe underlying immune deficiency, especially in a young and otherwise healthy individual. However, if you have concerns about your immune health, pursuing a thorough evaluation with a healthcare professional is a prudent step. They can help you understand your immune status and provide guidance on any necessary lifestyle changes or treatments to support your immune system.

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