Long-Term Management of Chronic Urticaria: Do Patients Need Continuous Medication? - Dermatology

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Long-term treatment of chronic urticaria?


Hello Dr.
Lee! I am a patient with chronic urticaria.
Previously, while I was on medication, my hives improved and did not reappear, so I stopped taking the medication.
However, once I stopped, they recurred.
I would like to ask, is it necessary to undergo long-term medication treatment for chronic urticaria?

Wu, 20~29 year old female. Ask Date: 2017/04/04

Dr. Li Yufen reply Dermatology


Hello: For a detailed introduction to chronic urticaria, you can refer to the article on the Dermatology Expert Health Network at http://www.drskincare.com.tw/Qa/Index.aspx?CID=21.
The current treatment approach primarily involves antihistamines, and it is usually recommended to take the medication consistently for 3 to 6 months while managing stress appropriately, which can effectively improve symptoms.
Thank you!

Reply Date: 2017/04/04

More Info


Chronic urticaria, commonly known as chronic hives, is a condition characterized by the recurrent appearance of itchy welts or hives on the skin that can last for six weeks or longer. Managing this condition can be challenging, and many patients find themselves in a cycle of treatment and relapse. Your question about whether long-term medication is necessary for chronic urticaria is quite pertinent and reflects the experiences of many patients dealing with this condition.

To address your question directly: yes, many patients with chronic urticaria may require long-term medication to manage their symptoms effectively. The primary goal of treatment is to control symptoms and improve the quality of life. Antihistamines are the first-line treatment for chronic urticaria, and they work by blocking the action of histamine, a substance in the body that causes allergic symptoms. For some patients, standard doses of antihistamines may not be sufficient, and higher doses or a combination of different antihistamines may be necessary.

In cases where antihistamines alone do not provide adequate relief, other medications may be considered. These can include corticosteroids for short-term flare-ups, leukotriene receptor antagonists, or even biologic therapies such as omalizumab, which is specifically approved for chronic urticaria. Omalizumab is an injectable medication that can significantly reduce the severity and frequency of hives in patients who do not respond to traditional treatments.

It's important to note that chronic urticaria can be triggered by various factors, including stress, certain foods, medications, and environmental factors. Identifying and avoiding these triggers can be an essential part of managing the condition. Keeping a symptom diary can help you and your healthcare provider identify patterns and potential triggers.

Regarding the need for continuous medication, many patients find that stopping their antihistamines leads to a resurgence of symptoms. This is not uncommon, as chronic urticaria can be a persistent condition. Some patients may need to remain on medication for an extended period, while others may experience periods of remission where they can reduce or stop their medication without a return of symptoms. The decision to continue or discontinue medication should be made in consultation with a healthcare provider, who can assess your specific situation and determine the best course of action.

In summary, while some patients may experience improvement and be able to stop their medication, many will require long-term treatment to manage chronic urticaria effectively. Regular follow-up with a healthcare provider is crucial to monitor the condition, adjust treatment as necessary, and ensure that any potential side effects from long-term medication use are managed appropriately. If you are experiencing persistent symptoms, it would be advisable to discuss your treatment options with your healthcare provider, who can help tailor a management plan that suits your needs.

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