Endometrial issues
I have experienced irregular menstruation about 2-3 times a year for the past three years (my period returns about 10 days after it ends, and the second occurrence lasts for more than 10 days).
Is it possible to first perform an endometrial biopsy? (I am concerned about the need for general anesthesia for a dilation and curettage procedure.) I have heard that the accuracy of the biopsy is about 80-90%, which is significantly lower than the accuracy of a complete endometrial curettage.
If I do not want to undergo a complete curettage, can I initially use the biopsy method (sampling multiple areas of the endometrium) and still consider the accuracy? I have also read that some doctors suggest using hysteroscopy first to check for any issues, but there are concerns that if malignancy is present, using hysteroscopy directly could lead to the risk of spreading.
Is that true? Thank you!
Ailisi, 40~49 year old female. Ask Date: 2017/05/18
Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, I apologize for not being able to provide a diagnosis based on what you've described.
At 49 years old, irregular menstruation may be due to perimenopause.
It is acceptable to observe the situation for now.
If you wish to undergo further testing, I recommend discussing it in detail with your obstetrician-gynecologist.
Wishing you good health.
Reply Date: 2017/05/18
More Info
When it comes to understanding endometrial issues, particularly in the context of abnormal uterine bleeding, the choice between endometrial sampling (biopsy) and dilation and curettage (D&C) is an important consideration. Your concerns about the frequency of your menstrual irregularities and the associated diagnostic procedures are valid and warrant a detailed discussion.
Endometrial Sampling vs. D&C
1. Endometrial Sampling (Biopsy):
- This procedure involves taking small samples of the endometrial tissue for examination. It can often be performed in a doctor's office without the need for general anesthesia, which can alleviate some of the anxiety associated with surgical procedures.
- The accuracy of an endometrial biopsy is generally high, with reported sensitivity rates of 80-90%. This means that it can effectively identify conditions such as endometrial hyperplasia or cancer in a significant majority of cases.
- The procedure is less invasive than a D&C, making it a preferred first step for many clinicians when investigating abnormal uterine bleeding.
2. Dilation and Curettage (D&C):
- D&C is a surgical procedure that involves dilating the cervix and scraping the entire lining of the uterus. This is typically performed under general anesthesia.
- While D&C can provide a more comprehensive sample of the endometrial lining, it is more invasive and carries risks associated with anesthesia and surgical complications.
- D&C is often reserved for cases where a more extensive evaluation is necessary, such as when there is a strong suspicion of malignancy or when a biopsy result is inconclusive.
Initial Diagnostic Approach
Given your history of irregular bleeding, starting with an endometrial biopsy is a reasonable approach. It allows for the collection of tissue samples from multiple areas of the endometrium, which can provide valuable information without the need for more invasive procedures. If the biopsy results are inconclusive or if there are significant findings that warrant further investigation, a D&C may then be considered.
Use of Hysteroscopy
Hysteroscopy is another diagnostic tool that allows direct visualization of the uterine cavity. It can be used to identify abnormalities such as polyps, fibroids, or other lesions. While hysteroscopy can be very informative, there are concerns about the potential for spreading malignant cells if a cancerous lesion is present. This is why some practitioners may prefer to perform a biopsy first before proceeding with hysteroscopy, especially in cases where malignancy is a concern.
Conclusion
In summary, for your situation, starting with an endometrial biopsy is a sensible and less invasive option that can provide significant diagnostic information. If the biopsy indicates abnormalities or if further evaluation is needed, then a D&C or hysteroscopy can be considered. It is essential to have a thorough discussion with your healthcare provider about your symptoms, concerns, and the best approach tailored to your specific situation. They can help guide you through the options, ensuring that you are comfortable and informed about the procedures involved.
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