The possibility of angina pectoris?
Hello Doctor: I do not smoke or drink and my overall health check-up shows normal total cholesterol, normal high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol levels, and normal triglycerides.
However, I often experience chest tightness.
I visited a cardiologist at the hospital, and the results of the standard electrocardiogram were normal.
The 24-hour Holter monitor and echocardiogram indicated mitral valve prolapse, and my heart rate occasionally fluctuates.
During an exercise electrocardiogram, I experienced hypoxia when my heart rate reached 160-170 beats per minute.
Due to my anxiety disorder, I constantly worry about the possibility of a myocardial infarction.
Therefore, I am considering undergoing a cardiac CT angiography, but I found online that the procedure requires the injection of a contrast agent, which is not recommended for individuals with poor kidney function.
Additionally, the contrast agent could potentially cause severe allergic reactions leading to shock.
My health report shows a serum creatinine level of 1.2 mg/dL and a glomerular filtration rate (GFR) of 81 mL/min, indicating slightly impaired kidney function.
I am unsure why, at only 30 years old, I have this condition, which raises my concerns about the safety of receiving a contrast agent.
I also worry that my body may react unusually and cause severe allergic reactions.
Is it appropriate for me to undergo cardiac CT angiography under these circumstances? The cardiologist prescribed two medications for the prevention of angina: Nirandil and Coxine, suggesting that I take them and observe my condition.
The doctor believes there is a possibility of angina, but given my young age, he thinks the likelihood is low.
He also mentioned that it might not be angina but rather one of the following possibilities: naturally smaller or more sensitive blood vessels, microcirculation disorders, or myocardial bridging.
If any of these are the case, what risks might be involved? My question is whether the two medications prescribed by the cardiologist could potentially improve my condition and normalize the exercise electrocardiogram after a month of observation.
Is the risk of myocardial infarction high? Lastly, I would like to ask if I am suitable for exercise and whether I need to monitor my heart rate during physical activity.
I apologize for the lengthy questions and appreciate your time in responding! Thank you, Doctor!
Andrew, 30~39 year old female. Ask Date: 2017/05/29
Dr. He Dongjin reply Cardiology
Hello,
1.
It is difficult to say whether a specific constitution may lead to severe anaphylactic shock, but the probability is low.
If necessary, isotonic contrast agents can be used.
2.
Exercise stress tests can yield false positives, so it does not necessarily indicate the presence of coronary artery disease.
You can ask your physician to calculate the Duke Treadmill Score for risk assessment.
If the score indicates low risk, there is no need to worry; just monitor your condition.
Some individuals may naturally have smaller or more sensitive blood vessels, or issues like microcirculation disorders or myocardial bridging, which carry a very low risk.
3.
Taking medication will not improve the subsequent exercise stress test results to normal.
4.
It is suitable for you to exercise! Engage in any activity that does not cause discomfort.
There is no need to control your heart rate during exercise.
Changhua Hospital cares about you.
Reply Date: 2017/05/29
More Info
Understanding angina, its risks, diagnosis, and treatment options is crucial, especially for someone like you who is experiencing chest discomfort and has a history of anxiety. Let's break down your concerns and provide a comprehensive overview.
Angina Overview
Angina is a type of chest pain caused by reduced blood flow to the heart muscles. It is often a symptom of coronary artery disease (CAD), which can lead to more severe conditions like heart attacks. There are two main types of angina: stable and unstable. Stable angina occurs with exertion and is relieved by rest, while unstable angina can occur at rest and may signal a more serious condition.
Risks and Diagnosis
Given your healthy lifestyle—non-smoker, non-drinker, and normal cholesterol levels—your risk factors for coronary artery disease seem low. However, the presence of mitral valve prolapse (MVP) and episodes of tachycardia (rapid heart rate) can contribute to your symptoms. The fact that you have anxiety can also exacerbate feelings of chest discomfort, leading to a cycle of worry about heart conditions.
Your tests, including a standard ECG, 24-hour Holter monitor, and echocardiogram, did not reveal significant abnormalities, which is reassuring. However, the exercise stress test indicating oxygen deprivation at high heart rates is concerning and warrants further investigation.
Concerns About CT Angiography
You mentioned considering a coronary CT angiography (CTA) but are worried about the use of contrast agents due to your slightly impaired kidney function (creatinine of 1.2 mg/dL and GFR of 81 ml/min). While contrast-induced nephropathy is a risk, many patients with mild renal impairment undergo CTA without significant issues. It’s essential to discuss your concerns with your cardiologist, who can assess your specific risk and may consider alternative imaging methods if necessary.
Medication and Treatment Options
Your cardiologist prescribed Nirandil and Coxine, which are used to manage angina and improve blood flow. These medications can help alleviate your symptoms and potentially improve your exercise tolerance. It’s important to monitor how you feel while on these medications and report any changes to your doctor.
If your symptoms improve with medication, it may indicate that your chest discomfort is indeed related to angina rather than other causes. However, if your symptoms persist or worsen, further evaluation may be necessary.
Exercise and Lifestyle
Regarding exercise, it is generally beneficial for heart health, but you should approach it cautiously given your symptoms. Start with low-intensity activities and gradually increase as tolerated. Monitoring your heart rate during exercise is wise; aim to stay within a safe range as advised by your healthcare provider. If you experience chest pain, dizziness, or significant shortness of breath during exercise, stop immediately and seek medical attention.
Conclusion
In summary, while your symptoms may be concerning, the combination of a healthy lifestyle, normal cholesterol levels, and thorough cardiac evaluations suggests that you may not be at high risk for severe heart disease. However, your anxiety and the potential for MVP-related symptoms can complicate your situation.
Continue to work closely with your cardiologist, follow their recommendations regarding medication and lifestyle changes, and don’t hesitate to express any concerns you have about your treatment plan. Regular follow-ups will be essential in managing your condition effectively. Remember, it’s crucial to listen to your body and seek help whenever you feel uncertain about your health.
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