Drug Interactions and Dietary Restrictions: A Guide for Patients in Taiwan - Pharmacology

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Chuan Li Ning and Wei Gu Li?


1.
The medications I am taking include Xunli Ning, Bone Strength, sleeping pills, vitamin B, and a multivitamin.
I also regularly drink ginseng tea.
Which of these should not be taken together?
2.
My husband is taking Novartis's Caduet and Glucophage.
Can he take Xunli Ning as well?
3.
Are there any food interactions or contraindications with all the medications mentioned above? For example, grapefruit, etc.
Please advise.
Thank you for your service.

GOGO, 60~69 year old female. Ask Date: 2017/06/07

Dr. Liu Huiya reply Pharmacology


There are no clear reports indicating adverse effects from the concurrent use of Xunli Ning, Bone Strength, sleeping pills, vitamin B, and multivitamins with ginseng tea; however, please do not exceed the recommended dosage.
When taking Novartis's Xiclipid and Glucophage, there are also no clear reports indicating adverse effects from the concurrent use of Xunli Ning, but please adhere to the recommended dosages.
However, when using Xiclipid, it is advised to avoid grapefruit (juice) and cranberry juice, as reports suggest that these two may increase the bioavailability of Xiclipid, thereby increasing the risk of muscle disorders or rhabdomyolysis.

Reply Date: 2017/06/07

More Info


When it comes to drug interactions and dietary restrictions, it's crucial for patients to be well-informed about the medications they are taking and how they may interact with each other and with certain foods. Here, I will address your questions regarding the medications you mentioned, as well as provide general guidance on avoiding potential interactions.

1. Drug Interactions with Your Medications: You mentioned taking "循利寧" (likely referring to a medication for hypertension or heart conditions), "維骨力" (which may be a supplement for bone health), sleep medications, vitamin B, and a multivitamin, along with drinking ginseng tea.
- 循利寧 (likely a beta-blocker or similar): This medication can interact with other drugs that lower blood pressure. It is generally advisable to avoid taking it with other antihypertensives without medical supervision.

- 維骨力: If this is a calcium supplement, it may interfere with the absorption of certain medications, particularly those that are taken orally. It's best to space out calcium supplements from other medications by at least two hours.

- Sleep medications: These can have sedative effects, and combining them with other sedatives (including alcohol or certain antihistamines) can increase the risk of excessive sedation.

- Ginseng tea: Ginseng can potentially affect blood sugar levels and may interact with medications for diabetes or blood pressure. It is generally recommended to monitor blood sugar levels closely if you are taking ginseng while on diabetes medications.

2. Regarding Your Husband's Medications: If your husband is taking "諾華喜克脂" (likely a statin for cholesterol management) and "醣祿錠" (which may be a diabetes medication), it is essential to consult with a healthcare provider before introducing "循利寧." Statins can have interactions with certain blood pressure medications, and the combination should be monitored by a physician to avoid potential side effects.

3. Food Interactions: Regarding dietary restrictions, certain foods can indeed interact with medications:
- Grapefruit: This fruit is known to interact with many medications, particularly statins and some blood pressure medications, by affecting the enzymes that metabolize these drugs. It can lead to increased levels of the medication in the bloodstream, raising the risk of side effects.

- High-fiber foods: While generally healthy, they can affect the absorption of certain medications if taken simultaneously. It’s advisable to take medications at least one hour before or two hours after consuming high-fiber meals.

- Alcohol: This can interact with many medications, including sleep aids and blood pressure medications, leading to increased sedation or other adverse effects.

General Recommendations:
- Always take medications as prescribed by your healthcare provider and discuss any concerns about interactions with them.

- Maintain a consistent schedule for taking medications and supplements to avoid potential interactions.

- Keep a list of all medications, supplements, and herbal products you are taking and share this with your healthcare provider during visits.

- If you experience any unusual symptoms or side effects after starting a new medication or supplement, contact your healthcare provider immediately.

In conclusion, while the medications you are taking can be beneficial for your health, it is essential to be aware of potential interactions with each other and with certain foods. Regular communication with your healthcare provider and pharmacist can help ensure that you are managing your medications safely and effectively.

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