Effectiveness of Emergency Contraceptives with Other Medications - Obstetrics and Gynecology

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Emergency contraceptive pills and other medications?


I am currently taking Lickang, Aidasin, and the pre-conception contraceptive Wenbunin 28 due to menstrual issues, all prescribed by my doctor.
I would like to ask if this contraceptive still has efficacy and whether there might be reduced effectiveness due to drug interactions.
I have been taking the contraceptive for one week in the first month.
Thank you for your response, doctor!

ni逆, 20~29 year old female. Ask Date: 2017/06/14

Dr. Huang Jianzhong reply Obstetrics and Gynecology


I am currently taking Licozene, Adacel, and Wenbunin 28 due to menstrual issues, all prescribed by my doctor.
I would like to ask if the contraceptive pill is still effective under these circumstances, and whether there might be any drug interactions that could reduce its efficacy.
I have been taking the contraceptive for one week in the first month.
Answer: Licozene, Adacel, and Wenbunin 28 are all prescribed for the treatment of polycystic ovary syndrome; you only need to choose one.

Reply Date: 2017/06/14

More Info


When considering the effectiveness of emergency contraceptives (EC) in conjunction with other medications, it is crucial to understand how various drugs can interact and potentially affect the efficacy of hormonal contraceptives. In your case, you are taking medications for your menstrual issues, specifically Likozan (likely referring to a medication that addresses hormonal balance) and Eda-Sin (which may be a brand name for a medication that affects menstrual cycles), along with a regular contraceptive pill.

Emergency contraceptives, such as those containing levonorgestrel or ulipristal acetate, work primarily by delaying ovulation. Their effectiveness can be influenced by several factors, including the timing of administration relative to ovulation, body weight, and the presence of other medications.

1. Drug Interactions: Some medications can induce liver enzymes that metabolize hormonal contraceptives, potentially reducing their effectiveness. For example, certain anticonvulsants, antibiotics (like rifampicin), and herbal supplements (like St. John's Wort) can lead to decreased levels of contraceptive hormones in the bloodstream. However, most common medications, including those for menstrual issues, do not typically have this effect.

2. Likozan and Eda-Sin: Without specific details on these medications, it is difficult to provide a precise answer. However, if these medications are hormonal treatments or related to menstrual regulation, they may not significantly interfere with the effectiveness of your emergency contraceptive. It is essential to consult with your healthcare provider or pharmacist regarding the specific interactions of these medications with your contraceptive.

3. Timing and Administration: The effectiveness of emergency contraceptives is highest when taken as soon as possible after unprotected intercourse. If you have already been taking your regular contraceptive pill consistently for a week, it should provide a baseline level of hormonal protection. However, if you are relying on emergency contraception due to a missed dose or unprotected intercourse, the timing of taking the EC is critical.

4. Consulting Healthcare Providers: Given that you are on multiple medications, it is advisable to discuss your specific situation with your healthcare provider. They can provide personalized advice based on your medical history, the specific medications you are taking, and any potential interactions.

5. Monitoring for Side Effects: While taking multiple medications, be vigilant for any unusual side effects or changes in your menstrual cycle. If you experience significant changes or have concerns about the effectiveness of your contraceptive method, seek medical advice promptly.

In conclusion, while the medications you are taking may not significantly reduce the effectiveness of your emergency contraceptive, it is essential to consult with your healthcare provider for tailored advice. They can help clarify any potential interactions and ensure that you are adequately protected against unintended pregnancy. Always prioritize open communication with your healthcare team regarding all medications you are taking to ensure safe and effective treatment.

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