Persistent Mouth Sores: Causes and Treatment Options Explained - Otolaryngology

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Mouth sores have not healed for two weeks?


Recently, I had two sores in my mouth; the one on the upper left has healed, but the two on my lower lip haven't improved for two weeks.
I visited an ENT specialist, who prescribed a medication that resembles iodine (dark red).
In the past, applying it was very painful, but this time I didn't feel anything when applying it, and the wound doesn't hurt (it doesn't hurt during the day either, but the area that is broken still has a white substance).
I've been applying the medication for a week, but it hasn't healed.
Are there any other issues?

4a12c095, 20~29 year old female. Ask Date: 2017/06/16

Dr. Zheng Jueyi reply Otolaryngology


Hello, if there is no improvement, it is recommended to continue follow-up visits or go to the hospital to assess whether a biopsy is necessary.
Wishing you safety and health.
Sincerely, Dr.
Cheng Jue-Yi, Director of the Department of Otolaryngology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2017/06/16

More Info


Persistent mouth sores can be a frustrating and painful experience, and understanding their causes and treatment options is essential for effective management. Mouth sores, also known as oral ulcers, can arise from various factors, including trauma, infections, autoimmune conditions, and systemic diseases.

Causes of Persistent Mouth Sores
1. Trauma: Accidental bites, aggressive brushing, or dental work can cause sores that may take time to heal, especially if the area is repeatedly irritated.

2. Infections: Viral infections, such as herpes simplex virus, can lead to painful sores. Fungal infections like oral thrush can also cause white patches and discomfort in the mouth.

3. Autoimmune Conditions: Conditions such as Behçet's disease, lupus, or pemphigus vulgaris can cause recurrent mouth sores as part of a broader systemic issue.

4. Nutritional Deficiencies: Deficiencies in vitamins, particularly B vitamins (B12, folate) and minerals like iron and zinc, can lead to the development of mouth sores.

5. Systemic Diseases: Conditions like Crohn's disease or ulcerative colitis can manifest oral symptoms, including persistent sores.

6. Allergic Reactions: Allergies to certain foods, medications, or dental products can lead to mucosal irritation and sores.

7. Stress: Emotional stress can exacerbate existing conditions or trigger new outbreaks of mouth sores.


Treatment Options
1. Topical Treatments: Over-the-counter topical anesthetics can provide temporary relief from pain. Prescription medications, such as corticosteroids, can reduce inflammation and promote healing. The iodine-based solution you mentioned is likely an antiseptic that helps prevent infection but may not directly promote healing.

2. Oral Rinses: Antimicrobial mouthwashes can help reduce bacteria in the mouth and promote healing. Rinses containing dexamethasone or lidocaine may also be prescribed to alleviate pain and inflammation.

3. Nutritional Supplements: If deficiencies are suspected, dietary adjustments or supplements may be necessary to address underlying nutritional issues.

4. Avoiding Irritants: Identifying and avoiding potential irritants, such as spicy foods, alcohol, and tobacco, can help reduce the frequency and severity of mouth sores.

5. Managing Underlying Conditions: If an autoimmune disease or systemic condition is identified, managing that condition with the help of a healthcare provider is crucial for reducing the occurrence of mouth sores.

6. Regular Follow-ups: If sores persist beyond a few weeks, it is essential to follow up with a healthcare provider. They may recommend further diagnostic tests, such as blood tests or biopsies, to rule out more serious conditions.


When to Seek Further Medical Attention
If your mouth sores do not improve after two weeks, or if you experience additional symptoms such as fever, difficulty swallowing, or significant pain, it is important to seek further evaluation. A healthcare provider may consider additional diagnostic tests to identify the underlying cause and tailor a more effective treatment plan.

In conclusion, persistent mouth sores can result from various causes, and understanding these can help in managing the condition effectively. Treatment options range from topical medications to addressing underlying health issues. If your symptoms persist or worsen, do not hesitate to consult a healthcare professional for a comprehensive evaluation and management plan.

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