Oral Mucosa Issues: White Spots and Immune Connection - Dentistry

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Oral mucosal issues


I would like to consult a doctor.
Recently, I noticed some small white spots inside my right cheek.
They appear when I open my mouth, and there are about two or three of them.
They are not raised lesions and look somewhat like a thin white membrane.
I am hesitant to use a cotton swab to touch them.
I would like to know if these will go away on their own.
Are they related to my immune system? I don't feel any discomfort.
Thank you for your response, doctor.

vivi, 40~49 year old female. Ask Date: 2017/06/20

Dr. Zhu Guanyu reply Dentistry


Dear Vivi,
If you have any unexplained lesions or sores in your mouth that persist for 2-3 weeks or even enlarge in size, it is recommended that you visit an otolaryngologist or oral surgeon for further examination and treatment.
Thank you for your message.

Wishing you peace and good health,
Dr.
Kuan-Yu Chu
Director of Dentistry
Taoyuan Hospital, Ministry of Health and Welfare

Reply Date: 2017/06/20

More Info


The presence of white spots in the oral mucosa, particularly when they appear as thin membranes or patches, can be indicative of several conditions, including oral thrush (candidiasis), leukoplakia, or even oral lichen planus. Given your description of the spots being flat and not raised, it is essential to consider the context of your overall health, including any potential immune system issues.

Oral thrush is a fungal infection caused by the overgrowth of Candida species, which can occur when the immune system is compromised. Factors that can lead to a weakened immune response include stress, certain medications (like corticosteroids or antibiotics), and underlying health conditions such as diabetes or HIV. Although you mentioned that you have not engaged in high-risk behaviors or have any known health issues, it is still possible for oral thrush to develop in otherwise healthy individuals, especially if there are changes in the oral environment, such as poor oral hygiene or dry mouth.

Leukoplakia, on the other hand, is characterized by white patches that cannot be scraped off and may be a response to chronic irritation, such as from tobacco use or ill-fitting dentures. While you do not have a history of tobacco use or dentures, leukoplakia can also occur in individuals with a history of oral trauma or irritation.

Oral lichen planus is another condition that can present with white patches in the mouth. It is an inflammatory condition that can be associated with stress and immune system dysregulation. The exact cause is not fully understood, but it is believed to involve an autoimmune response.

In terms of whether these spots will resolve on their own, it largely depends on the underlying cause. If they are due to a benign condition, such as a minor irritation or a transient fungal infection, they may indeed resolve without intervention. However, if they persist for more than two weeks or are accompanied by other symptoms (such as pain, difficulty swallowing, or changes in taste), it is crucial to seek further evaluation from a healthcare professional.

Regarding the connection to immune function, yes, the immune system plays a significant role in maintaining oral health. A compromised immune system can lead to an imbalance in the oral microbiome, allowing opportunistic infections like oral thrush to take hold. Conversely, conditions that cause chronic inflammation or immune dysregulation can lead to changes in the oral mucosa, resulting in lesions or patches.

In conclusion, while the white spots you are observing may not be a cause for immediate concern, it is essential to monitor them closely. Maintaining good oral hygiene, managing stress, and ensuring a balanced diet can support your immune health and potentially prevent further issues. If the spots do not resolve or if you experience any new symptoms, please consult a dentist or an oral health specialist for a thorough examination and appropriate management.

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