GERD Medications: Side Effects and Recovery Options - Gastroenterology and Hepatology

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Issues with Gastroesophageal Reflux Disease (GERD) Medications


Hello Dr.
Chen, I underwent an upper gastrointestinal endoscopy in April of this year, which revealed a relaxed lower esophageal sphincter causing gastroesophageal reflux disease (GERD).
The doctor prescribed Strocain, Domperidone to be taken before meals, and Sennosides PTP to be taken at bedtime.
However, I have recently experienced headaches after taking the medication.
I would like to know which medication might be causing the headache as a side effect, and whether I should inform my doctor to switch to a different medication.
Given my age, is it possible for the relaxed lower esophageal sphincter to recover on its own? Additionally, can Domperidone help in the recovery of the lower esophageal sphincter? Thank you.

Mr. Ren, 20~29 year old female. Ask Date: 2017/07/12

Dr. Chen Qifeng reply Gastroenterology and Hepatology


1) It is recommended to discontinue Strocain and Domperidone.
2) Gastroesophageal reflux can be treated, but it is prone to recurrence.
There are no medications that can completely cure it; they can only improve function.

Reply Date: 2017/07/12

More Info


Hello! Thank you for your inquiry regarding your treatment for gastroesophageal reflux disease (GERD) and the medications you are currently taking. Let's break down the medications you've mentioned, their potential side effects, and discuss your concerns about recovery.


Medications Overview
1. Strocain (also known as Benzocaine): This medication is often used as a local anesthetic to relieve pain. While it is not commonly associated with headaches, allergic reactions or sensitivity can occur in some individuals.

2. Domperidone: This medication is a dopamine antagonist that is primarily used to treat nausea and vomiting. It works by increasing the movement of food through the stomach and intestines, which can help alleviate symptoms of GERD. However, one of the potential side effects of Domperidone is headache, along with dizziness and dry mouth. If you are experiencing headaches, it's important to consider whether Domperidone could be the culprit.

3. Omelon (Omeprazole): This is a proton pump inhibitor (PPI) that reduces stomach acid production. While generally well-tolerated, some patients report side effects such as headaches, gastrointestinal disturbances, and, in rare cases, long-term use can lead to other complications like vitamin B12 deficiency or bone fractures.

4. Sennosides: This is a laxative used to treat constipation. It is not typically associated with headaches, but gastrointestinal discomfort can occur.


Side Effects and Headaches
Given your symptoms of headaches, it is most likely that either Domperidone or Omeprazole could be contributing to this side effect. It is advisable to inform your physician about these headaches, as they may consider adjusting your medication regimen or switching to an alternative that may be better tolerated.


Recovery and Management of GERD
Regarding your question about the possibility of spontaneous recovery of a relaxed lower esophageal sphincter (LES), it is essential to understand that while some individuals may experience improvement in their symptoms over time, others may require ongoing management. Factors such as diet, lifestyle changes, and medication adherence play a significant role in managing GERD effectively.

Domperidone can help improve gastric motility, which may indirectly support the function of the LES, but it is not a definitive treatment for a relaxed sphincter. Lifestyle modifications, such as avoiding trigger foods (spicy, fatty, or acidic foods), eating smaller meals, and not lying down immediately after eating, can also be beneficial.


Recommendations
1. Consult Your Doctor: Since you are experiencing headaches, it is crucial to discuss this with your healthcare provider. They may want to evaluate your current medication regimen and consider alternatives.

2. Lifestyle Modifications: Implement dietary changes, maintain a healthy weight, and avoid lying down after meals to help manage GERD symptoms.

3. Follow-Up: Regular follow-ups with your healthcare provider are essential to monitor your condition and adjust treatment as necessary.

4. Consider Other Therapies: If medication adjustments do not alleviate your symptoms, your doctor may discuss other treatment options, including surgical interventions, especially if the reflux is significantly impacting your quality of life.

In conclusion, while some individuals may experience improvement in their condition, it is essential to work closely with your healthcare provider to manage your symptoms effectively and address any side effects you may be experiencing. Thank you for reaching out, and I wish you the best in your recovery!

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