Low-Risk HPV and Its Connection to Genital Warts - Obstetrics and Gynecology

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Low-risk human papillomavirus associated with cauliflower?


Hello Doctor, last April I noticed some unusual flat protrusions in my genital area and suspected they might be warts, so I visited a large hospital for a consultation.
After an internal examination, the doctor believed they were either pseudowarts or congenital (they have always been like this, but I was unaware).
However, I was not reassured, so I underwent a human papillomavirus (HPV) test, which came back negative with very low values, finally putting my mind at ease.
Recently, though, I noticed that the area of the flat protrusions seems to have increased.
Although they are not itchy or painful, I reviewed my previous test report and found that it tested for high-risk HPV types, but the low-risk types 6 and 11, which could cause warts, were not included in the test.

I have a few questions:
1.
Is it possible that my symptoms could be warts? (flat protrusions, not itchy or painful, with clear or white discharge)
2.
Is there a screening available for the low-risk HPV types 6 and 11?
3.
What tests are more accurate for confirming warts? Thank you for your patient response!

Evelyn, 20~29 year old female. Ask Date: 2017/07/19

Dr. Zhang Kunmin reply Obstetrics and Gynecology


A physician cannot administer treatment, prescribe medication, or provide a diagnosis without a personal examination.
Hello, based on your description, a definitive diagnosis cannot be established.
The identification of warts relies on the appearance of the lesions, the site of infection, and confirmation through biopsy.
It is recommended that you visit a gynecology clinic for further examination and confirmation.
Thank you! Wishing you peace and health, Dr.
Chang.

Reply Date: 2017/07/19

More Info


Understanding Low-Risk HPV and Its Connection to Genital Warts
Human Papillomavirus (HPV) is a group of more than 200 related viruses, some of which are classified as low-risk and others as high-risk. Low-risk HPV types, particularly types 6 and 11, are primarily associated with the development of genital warts, also known as condylomata acuminata or "cauliflower-like" lesions. These warts can appear as small, flesh-colored or gray swellings in the genital area and may be raised or flat.
1. Could Your Symptoms Be Genital Warts?
Given your description of the symptoms—specifically the presence of raised, patchy growths that are not itchy or painful—it is possible that you are experiencing genital warts. However, the definitive diagnosis of genital warts typically requires a clinical examination by a healthcare provider. The fact that you have previously tested negative for HPV and that the types associated with warts (6 and 11) were not included in your testing raises some questions. It is important to note that HPV testing is not routinely performed for low-risk types, as they are not associated with cancer. Therefore, a visual examination by a healthcare professional is often the most reliable method to determine if the lesions are indeed genital warts.

2. Is There Testing for Low-Risk HPV Types?
Currently, there is no standard test available for low-risk HPV types like 6 and 11 in the same way that there are tests for high-risk types associated with cervical cancer. Most HPV tests focus on high-risk types due to their association with cancer. If you are concerned about the possibility of low-risk HPV, it may be beneficial to discuss your symptoms with a healthcare provider who can perform a physical examination and provide guidance on the next steps. They may also consider a biopsy of the lesions if there is uncertainty regarding their nature.

3. What Are the Most Accurate Tests for Diagnosing Genital Warts?
The most accurate method for diagnosing genital warts is through a physical examination by a qualified healthcare provider. They will look for characteristic signs of warts, which can often be identified visually. In some cases, acetic acid (vinegar) may be applied to the lesions to enhance visibility, as warts may turn white when exposed to acetic acid. If there is any doubt about the diagnosis, a biopsy may be performed to rule out other conditions or to confirm the presence of HPV.

In summary, while low-risk HPV types like 6 and 11 are associated with genital warts, the absence of these types in your previous testing does not completely rule out the possibility of warts. It is essential to consult with a healthcare provider for a thorough examination and to discuss your symptoms. They can provide you with the most accurate diagnosis and recommend appropriate treatment options if necessary.
Additionally, it is important to remember that many HPV infections, including low-risk types, can be cleared by the immune system over time. Regular follow-ups and monitoring are crucial, especially if you notice any changes in your symptoms or the appearance of new lesions. If you are sexually active, practicing safe sex, including the use of condoms, can help reduce the risk of HPV transmission, although it does not provide complete protection. Vaccination against HPV is also an effective preventive measure and is recommended for both males and females to protect against the most common high-risk and low-risk HPV types.

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