Blood Test Results: When to Seek Medical Advice - Family Medicine

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Blood Issues in Health Check Reports


Hello Doctor, I have a hepatitis B carrier status and polycystic ovary syndrome.
I underwent a health check in early June, and some results were flagged in red.
The report shows: PLT (platelet count) 114, MPV (mean platelet volume) 10.4, PDW (platelet distribution width) 18.2, LY (lymphocyte percentage) 18.5, urine occult blood 1+, and blood urea nitrogen 6.
I would like to ask which specialty I should consult regarding my current condition, or if there are any specific concerns I should be aware of.
Thank you.

mini NANA, 30~39 year old female. Ask Date: 2017/07/20

Dr. Chen Taicheng reply Family Medicine


- Low platelet count may be caused by hepatitis B leading to splenomegaly, which consumes platelets.
- An increased platelet distribution width is a nonspecific abnormality and does not require concern.
- Mean Platelet Volume (MPV): A decrease in MPV may be associated with aplastic anemia or rheumatoid arthritis; an increase in MPV may be related to acute coronary syndrome or immune-mediated thrombocytopenia.
However, your condition seems to be related to hepatitis B.
- Urinary occult blood can be monitored; urinary tract infections are common in females.
- The lymphocyte percentage (LY) is slightly low at 18.5; if there are no signs of infection, observation is sufficient.
- Blood urea nitrogen is 6, which is slightly low but still within normal limits.
- It is recommended to have all reports reviewed by a family medicine or gastroenterology physician for a comprehensive interpretation to avoid any oversight.
Wishing you good health, Dr.
Chen Tai-Cheng from Taoyuan Hospital Family Medicine Department cares for you.

Reply Date: 2017/07/20

More Info


Understanding blood test results can be quite complex, especially when there are multiple indicators that fall outside the normal range. In your case, you have reported several abnormal values, including a low platelet count (PLT), a low lymphocyte percentage (LY), and the presence of blood in urine (urine occult blood). Given your medical history of hepatitis B and polycystic ovary syndrome (PCOS), it is essential to interpret these results carefully and seek appropriate medical advice.


Key Indicators from Your Report
1. Platelet Count (PLT): Your platelet count is reported at 114, which is below the normal range (typically 150-450 x 10^9/L). A low platelet count, known as thrombocytopenia, can result from various causes, including bone marrow disorders, liver disease, or autoimmune conditions. Given your history of hepatitis B, it is crucial to evaluate liver function and its potential impact on platelet production.

2. Mean Platelet Volume (MPV): Your MPV is 10.4, which is within the normal range. MPV can provide insight into platelet production; larger platelets may indicate increased production in response to low platelet counts.

3. Platelet Distribution Width (PDW): A PDW of 18.2 is slightly elevated. This measurement reflects the variability in platelet size and can indicate a response to platelet destruction or production issues.

4. Lymphocyte Percentage (LY): Your lymphocyte percentage is 18.5, which is lower than the typical range (20-40%). Lymphocytes are a type of white blood cell crucial for immune response. A low percentage may suggest an underlying issue with immune function or a response to infection or inflammation.

5. Urine Occult Blood: The presence of 1+ blood in urine can indicate various conditions, ranging from urinary tract infections (UTIs) to kidney stones or more serious renal issues. This finding warrants further investigation.

6. Blood Urea Nitrogen (BUN): A BUN level of 6 is generally considered normal, indicating that your kidney function is likely stable at this point.


Recommendations for Next Steps
Given the abnormalities in your blood test results, it is advisable to consult with a healthcare professional who specializes in hematology or internal medicine. Here are some specific steps you can take:
1. Hematologist Consultation: A hematologist can provide a thorough evaluation of your blood counts, particularly the low platelet count and lymphocyte percentage. They may recommend additional tests, such as a bone marrow biopsy or specific blood tests to rule out conditions like aplastic anemia or other hematological disorders.

2. Liver Function Tests: Since you have a history of hepatitis B, it would be prudent to have liver function tests performed to assess the health of your liver. This can help determine if your liver is contributing to the low platelet count.

3. Urology Consultation: Given the presence of blood in your urine, a urologist should evaluate this finding. They may perform imaging studies or a cystoscopy to investigate the source of the bleeding.

4. Monitoring and Follow-Up: Regular monitoring of your blood counts and liver function is essential. If your platelet count continues to drop or if you experience any symptoms such as easy bruising, bleeding, or fatigue, seek immediate medical attention.


Conclusion
In summary, your blood test results indicate several areas of concern that warrant further investigation. It is crucial to consult with specialists in hematology and urology to address these abnormalities comprehensively. Early intervention can lead to better outcomes, especially considering your existing health conditions. Always ensure that you communicate your medical history and any symptoms you may be experiencing to your healthcare providers for the best possible care.

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