Frequent Bacterial Infections: Is It a Sign of Immune System Issues? - Internal Medicine

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Repeated bacterial infections – is it a problem with the immune system?


Hello, doctor.
In mid-May of this year, I had an acne wound infection that spread inflammation to half of my face within a week.
After taking antibiotics for three weeks, I recovered.
Shortly after, at the end of May, I experienced an unexplained fever for three days, followed by severe itching above my arms and neck, accompanied by persistent erythema.
I was diagnosed with rubella and recovered about two weeks later.
During June, I developed multiple ulcers in my mouth and on my tongue, with noticeable swelling and bite marks on my tongue.
Additionally, when lying flat, I experienced severe intracranial pressure sensations if I pressed on my chest.
In mid-July, I developed a stye, which healed about a week later.
At the beginning of August, I had an unexplained outer ear canal infection, which is currently being treated.

In just three months, I have had multiple bacterial infections, and I am very confused about whether this is normal.
During this period, I have also experienced significant weight gain.
Therefore, I would like to ask if you recommend any tests, and which specialty I should consult?

Wu Chun, 20~29 year old female. Ask Date: 2017/08/14

Dr. Gao Jiankai reply Internal Medicine


Hello, thank you for your inquiry.
The frequent infections during this period are indeed unusual.
It is recommended to consult with an immunologist or a hematologist.
The Changhua Hospital of the Ministry of Health and Welfare has an Allergy, Immunology, and Rheumatology Department that can assist you.

Reply Date: 2017/08/14

More Info


Frequent bacterial infections can indeed be a concerning sign and may indicate underlying issues with your immune system. Given your recent history of multiple infections, including a severe acne infection that spread, German measles, oral ulcers, and external ear infections, it is understandable that you are worried about your immune health.

The immune system is a complex network of cells, tissues, and organs that work together to defend the body against harmful pathogens, including bacteria, viruses, and fungi. When the immune system is functioning properly, it can effectively respond to infections. However, recurrent infections can suggest that the immune system is not responding adequately, which could be due to various factors, including genetic predispositions, underlying health conditions, or environmental influences.

In your case, the sequence of events you described raises several questions. The initial acne infection that led to significant inflammation and swelling could indicate a compromised skin barrier or an overwhelming bacterial load. Following that, the diagnosis of German measles, which is a viral infection, suggests that your immune system was already under stress. The subsequent oral ulcers and external ear infections further point to a potential issue with your immune response.

There are several potential causes for recurrent infections, including:
1. Primary Immunodeficiency Disorders: These are genetic conditions that affect the immune system's ability to function properly. They can lead to increased susceptibility to infections.

2. Secondary Immunodeficiency: This can occur due to various factors such as chronic illnesses (like diabetes or HIV), certain medications (like corticosteroids or chemotherapy), or malnutrition.

3. Autoimmune Disorders: Conditions where the immune system mistakenly attacks the body can also lead to increased infections, as the immune system may be preoccupied with fighting itself rather than external pathogens.

4. Environmental Factors: Stress, lack of sleep, poor nutrition, and exposure to pathogens can all contribute to a weakened immune response.

Given your symptoms and the frequency of infections, it is advisable to seek a thorough evaluation. You should consider visiting an immunologist or a rheumatologist, as they specialize in immune system disorders and can conduct comprehensive tests to assess your immune function. Blood tests can evaluate various components of your immune system, including antibody levels, white blood cell counts, and complement levels.
Additionally, it may be beneficial to discuss your overall health, including any other symptoms you may have experienced, your medical history, and any family history of immune disorders. This information can help your healthcare provider determine the most appropriate tests and potential diagnoses.

In the meantime, maintaining a healthy lifestyle can support your immune system. This includes eating a balanced diet rich in fruits and vegetables, staying hydrated, getting regular exercise, managing stress, and ensuring adequate sleep. These factors can help bolster your immune response and overall health.

In summary, while experiencing multiple infections in a short period is not typical, it can be indicative of underlying immune system issues. A thorough evaluation by a specialist is recommended to determine the cause and appropriate management.

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