Fertility Issues: Managing Irregular Cycles and Treatment Options - Obstetrics and Gynecology

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Infertility-related issues


Hello, doctor.
Due to polycystic ovary syndrome (PCOS), I have been experiencing irregular menstruation.
Recently, I sought help from an infertility clinic.
Initially, I was required to have blood drawn three days before my expected period, but since my period did not arrive, the doctor prescribed Clomiphene Citrate (Wenbu Nuo 28) for 21 days to regulate my menstrual cycle.
After my period finally came, I underwent blood tests, hysteroscopy, and hysterosalpingography (HSG) (during these procedures, I took antibiotics, hemostatic agents, and pain relievers).
During my follow-up appointment to review the results, the doctor suggested starting with ovulation induction medication and asked me to return on the third day of my next period.
I informed the doctor that due to my irregular cycles, my period might not come for another three to four months, so the doctor prescribed Clomiphene Citrate (Wenbu Nuo 28) again for me to take for 21 days, advising me to return after my period to receive the ovulation medication.

I later discovered that Clomiphene Citrate is a contraceptive, but I have heard that after finishing a contraceptive, one should wait three months before trying to conceive.
Is this treatment plan normal? I hope the doctor can provide me with some advice.
Thank you.

abc, 30~39 year old female. Ask Date: 2017/08/15

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it seems that the treatment is currently proceeding normally.
Please follow your physician's instructions.
Wishing you good health.

Reply Date: 2017/08/15

More Info


When dealing with fertility issues, particularly in the context of polycystic ovary syndrome (PCOS) and irregular menstrual cycles, it's essential to understand both the medical rationale behind treatment options and the psychological implications of the journey.
PCOS is a common hormonal disorder that can lead to irregular menstrual cycles, making it challenging for women to conceive. The condition is characterized by a range of symptoms, including irregular periods, excess androgen levels, and polycystic ovaries. The hormonal imbalance can disrupt the normal ovulation process, leading to difficulties in achieving pregnancy.

In your case, the prescription of "温不妊28" (which appears to be a form of hormonal medication, possibly a combination of estrogen and progestin) is a common approach to regulate menstrual cycles. This medication is often used to mimic the natural menstrual cycle, helping to induce a period and potentially restore regular ovulation. While it is true that some forms of hormonal contraceptives can delay the return to fertility after discontinuation, the timeline can vary significantly among individuals.
The recommendation to take this medication for 21 days and then wait for your period to return before starting ovulation induction medications is a standard practice. The goal is to create a more predictable cycle, allowing for better timing of ovulation induction. It is not uncommon for doctors to prescribe hormonal treatments to regulate cycles before moving on to more direct fertility treatments, such as ovulation induction with medications like Clomiphene citrate or letrozole.

Regarding your concern about the use of birth control pills and the potential delay in achieving pregnancy, it is essential to note that while some women may experience a delay in ovulation after stopping hormonal contraceptives, many can conceive shortly after discontinuation. The three-month waiting period is often a guideline rather than a strict rule, and many women successfully conceive within the first few cycles after stopping birth control.

It is also crucial to maintain open communication with your healthcare provider. If you have concerns about the treatment plan or the medications prescribed, discussing these with your doctor can provide clarity and reassurance. They can explain the rationale behind each step of your treatment and adjust the plan as necessary based on your response and any side effects you may experience.

In addition to medical treatment, consider the psychological aspects of navigating fertility challenges. The emotional toll of irregular cycles and the uncertainty of conception can be significant. Support groups, counseling, or therapy can be beneficial in managing stress and anxiety related to fertility issues.
In summary, your treatment plan appears to be a standard approach for managing irregular cycles due to PCOS. While concerns about the use of hormonal medications are valid, many women successfully conceive after similar treatment regimens. It is essential to stay engaged with your healthcare provider, ask questions, and express any concerns you may have. Fertility treatment can be a complex journey, but with the right support and information, you can navigate it more effectively.

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