Can You Use AHA and Urea Together for Dry Skin? - Dermatology

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Can retinoic acid be used simultaneously with urea?


Hello, if using tretinoin causes excessive dryness and peeling, can urea be used simultaneously? Additionally, is it safe to use urea long-term? Thank you.

alice, 20~29 year old female. Ask Date: 2017/08/20

Dr. Wu Yuxin reply Dermatology


If there is obvious irritation, it is not recommended.
For long-term use, the concentration should be considered.

Reply Date: 2017/08/20

More Info


When it comes to managing dry skin, especially while using potent active ingredients like AHA (Alpha Hydroxy Acid) or A-acid (a form of retinoid), combining these with urea can be beneficial, but there are important considerations to keep in mind.

Using AHA and Urea Together:
AHA is known for its exfoliating properties, helping to remove dead skin cells and promote cell turnover. However, it can also lead to dryness and irritation, particularly for individuals with sensitive or already dry skin. Urea, on the other hand, is a humectant and keratolytic agent, which means it not only helps to hydrate the skin by drawing moisture in but also aids in softening and breaking down the outer layer of skin, making it an excellent choice for dry, flaky skin.

Combining AHA with urea can be effective, especially if you are experiencing excessive dryness and peeling from AHA use. Urea can help mitigate some of the dryness caused by AHA, making the skin feel more comfortable. However, it is crucial to monitor how your skin reacts to this combination. If you notice increased irritation or sensitivity, it may be best to separate their application. For instance, you could use AHA in the evening and apply urea in the morning or on alternate days.

Long-term Use of Urea:
Urea is generally safe for long-term use and is often found in various dermatological products designed for dry skin conditions, such as eczema or psoriasis. It can be particularly beneficial for maintaining hydration and improving skin texture over time. However, as with any active ingredient, it is essential to pay attention to your skin's response. If you notice any adverse effects, such as increased irritation or allergic reactions, it would be wise to consult a dermatologist.

Additional Considerations:
1. Patch Test: Before combining products, consider performing a patch test to ensure that your skin does not react negatively to the combination.

2. Moisturization: Regardless of the active ingredients you are using, maintaining a robust moisturizing routine is crucial. Look for moisturizers that contain occlusive agents (like petrolatum or dimethicone) to lock in moisture, especially after applying AHA or urea.

3. Sun Protection: AHA can increase your skin's sensitivity to the sun, so it is vital to apply sunscreen daily, particularly when using exfoliating acids.

4. Consultation with a Dermatologist: If you have persistent dryness or irritation, or if you are unsure about combining these products, consulting with a dermatologist can provide personalized advice tailored to your skin type and concerns.

In summary, using AHA and urea together can be beneficial for managing dry skin, but it is essential to monitor your skin's reaction and adjust your routine accordingly. Urea can be used long-term, but always ensure that your skin remains comfortable and hydrated.

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