Liver tumor treatment
Hello Dr.
Chen, a friend of mine was diagnosed with liver cancer last year.
After a year post-surgery for resection, a follow-up CT scan this year revealed a recurrence of liver cancer approximately 3 cm in the caudate lobe.
I consulted several surgeons; one said laparoscopic resection is possible, while another mentioned that due to the location and the previous surgery, the only option for now is to perform transarterial embolization (TAE).
I would like to ask Dr.
Chen, if the first surgeon says surgery is possible, can it really be done? If so, why wouldn’t the second surgeon proceed with it? If TAE is performed, how long should we wait to assess the effectiveness of the embolization? If the results of the embolization are not satisfactory, can surgery still be performed afterward?
A-Ba, 30~39 year old female. Ask Date: 2017/08/28
Dr. Chen Jiaming reply Surgery
Regarding the treatment and surgical indications for liver tumors, even among hepatobiliary surgeons, there can be differing opinions.
Some surgeons believe that if a liver tumor recurs and there is still a chance for resection (considering the expected functional status of the remaining liver), they will strive to pursue surgery.
Others argue that since recurrence suggests the possibility of multiple lesions (even if they have not yet manifested), they may first perform embolization to control the current tumor.
If subsequent follow-up reveals other multiple lesions that cannot be surgically eradicated, they will continue with embolization therapy (the advantage being the avoidance of physically exhausting surgeries that do not offer a curative benefit).
If, after the initial embolization treatment, follow-up confirms no new lesions have developed, surgery to resect the tumor in the caudate lobe can then be considered.
Embolization procedures effectively occlude the blood supply to the majority of tumors, which can significantly halt tumor progression; however, this is a control measure that requires repeated monitoring and may necessitate multiple interventions.
The choice of surgical technique (such as traditional surgery or laparoscopic surgery) depends on each surgeon's clinical experience and training, as well as the specific condition of the patient's liver and surrounding structures.
Tumors located deep within the liver, such as those in the caudate lobe, can be challenging to manage.
In some cases, patients who have previously undergone left lobectomy may find that the caudate lobe is more exposed; however, prior surgeries can lead to intra-abdominal adhesions, which indeed complicate the surgical procedure.
This information is for reference only.
It is essential to communicate and discuss with the clinical physician based on the patient's actual condition, as sometimes the timing for treatment can be missed if not addressed promptly.
Reply Date: 2017/08/28
More Info
When it comes to treating liver tumors, particularly in cases of recurrent liver cancer, the decision-making process can be complex and often involves multiple specialists. The treatment options generally include surgical resection, embolization, and sometimes other therapies such as ablation or systemic treatments. In your friend's case, the situation is further complicated by the recurrence of the tumor after a previous resection.
Surgical Resection vs. Embolization
1. Surgical Resection: This is often considered the gold standard for localized liver tumors, particularly if the tumor is resectable and the liver function is adequate. The fact that one surgeon suggested laparoscopic resection indicates that they believe the tumor is accessible and that the patient's overall health allows for surgery. However, the feasibility of surgery can depend on several factors, including the size and location of the tumor, the presence of underlying liver disease, and the patient's overall health status.
2. Embolization: This is a minimally invasive procedure that involves blocking the blood supply to the tumor, which can help shrink it or slow its growth. It is often used when surgery is not an option due to the tumor's location, size, or the patient's health. The second surgeon's recommendation for embolization suggests that they may have concerns about the risks associated with a second surgery, especially if there are adhesions or changes from the previous operation.
Why Different Opinions?
The differing opinions among surgeons can stem from their individual experiences, the specific characteristics of the tumor, and the patient's overall health. Some surgeons may be more aggressive in pursuing surgical options, while others may prioritize safety and recommend less invasive approaches first. It is not uncommon for medical professionals to have varying approaches to the same clinical scenario, especially in complex cases like liver cancer.
Evaluating Embolization Effectiveness
If embolization is performed, the effectiveness can typically be assessed through imaging studies, such as a follow-up CT scan or MRI, which may be done several weeks after the procedure. The exact timing can vary, but it is common to wait about 4 to 6 weeks to allow for adequate healing and to assess the response of the tumor to the embolization.
Next Steps if Embolization is Ineffective
If the embolization does not yield the desired results, surgical options may still be available, depending on the tumor's response and any changes in the patient's condition. If the tumor shrinks significantly, it may become resectable again. However, if the tumor remains stable or grows, further treatment options may need to be considered, including additional embolization, ablation techniques, or systemic therapies.
Conclusion
In summary, the treatment of recurrent liver tumors requires a careful evaluation of the tumor's characteristics, the patient's liver function, and overall health. It is essential for your friend to have a thorough discussion with their healthcare team to weigh the risks and benefits of each treatment option. A multidisciplinary approach, involving hepatologists, oncologists, and surgeons, can provide a comprehensive treatment plan tailored to the patient's specific situation. Regular follow-up and imaging are crucial to monitor the tumor's response to treatment and to make timely decisions about further interventions.
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