HPV, Warts, and Their Relationship: Key Questions Answered - Urology

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What is the relationship between HPV, HPV testing, and genital warts?


I have researched a lot of information online, and my personal understanding is that there are many types of HPV.
Most people infected with the HPV virus do not exhibit any symptoms and can spontaneously clear the virus within two years through their immune system.
Sometimes, when the virus cannot be cleared on its own, warts may develop, and those that appear on the genital area are referred to as "genital warts." Is this understanding correct? I have a few questions for the doctor:
1.
Doctors often say that the incubation period for genital warts cannot be detected by any means and can only be observed visually for three months.
Is this because even if HPV tests positive, it does not necessarily mean that genital warts will develop? Therefore, is there no significance in testing specifically for genital warts?
2.
If my HPV DNA test results are all negative (no virus), can I be certain that I do not have genital warts? If not, what is the significance of HPV DNA testing?
3.
If my HPV DNA test shows some positive types but I do not have any visible warts, should I not be overly concerned and instead allow my immune system to clear the virus, while monitoring and following up as scheduled?
4.
Is HPV DNA testing done through a blood sample? How long after suspecting that I may have contracted the virus should I get tested? One, two, or three months?

Niming, 20~29 year old female. Ask Date: 2017/08/29

Dr. Du Shixi reply Urology


Hello: 1.
Testing is used to assist in diagnosis; for example, if HPV is positive, it cannot determine when the infection occurred, only that there has been an infection in the past.
Certain types may have significance for cancer development in women.
2.
A negative result (due to the possibility of false negatives from different machines) should be discussed with a physician regarding the testing options (as different devices have different characteristics).
If the result is negative, the chance of having HPV is very, very low.
3.
If HPV DNA testing shows some types as positive but there are no warts present, is it reasonable not to worry too much and allow the immune system to clear the virus, while observing and following up regularly? --> Yes.
4.
HPV testing varies by machine and method, so it is important to consult with a physician (some can be done earlier, while others are chronic).
5.
Is it meaningful to have an HPV test when there are no warts? (It depends on the individual; some people are concerned, while others may not feel the need to test, as most people do not undergo testing.) Additionally, I would like to say that if some types are positive, I will exercise more to boost my immune system, and if all are negative, I can rule out the possibility of genital warts.
Is that correct? --> Yes, that is correct.
Additionally, it is important to practice safe sex.
This is the key point.

Reply Date: 2017/08/29

More Info


Understanding HPV, Warts, and Their Relationship: Key Questions Answered
Human Papillomavirus (HPV) is indeed a complex virus with over 100 different types, some of which can lead to genital warts, commonly referred to as "cauliflower" warts due to their appearance. Your understanding that most HPV infections are asymptomatic and can be cleared by the immune system within two years is correct. However, when the immune system does not clear the virus, it can lead to the development of warts or, in some cases, more serious conditions such as cervical or other genital cancers.

Now, let's address your specific questions:
1. Detection of Warts and HPV Testing: The reason why doctors often say that the incubation period for warts is around three months and that they cannot be detected through testing is that HPV can remain dormant in the body without causing any visible symptoms. While HPV testing can identify the presence of the virus, it does not necessarily correlate with the presence of warts. Therefore, if you test positive for HPV, it does not mean you will develop warts. This is why visual examination is critical in diagnosing warts; they can only be confirmed through physical observation.

2. Negative HPV DNA Test and Warts: If your HPV DNA test results are entirely negative, it is a strong indication that you do not have an active HPV infection, and therefore, you would not have warts. However, it is important to note that some types of HPV can be transient, meaning they can be present for a short time and then cleared by the immune system. Thus, while a negative test is reassuring, it does not provide a 100% guarantee against future infections.

3. Positive HPV DNA Test Without Warts: If your HPV DNA test shows positive results for certain types but you do not have visible warts, it is generally advisable to monitor the situation. Many HPV infections are cleared by the immune system without causing any health issues. Regular follow-up and monitoring are essential, as your healthcare provider may recommend periodic testing to ensure that the virus does not lead to any complications.

4. HPV DNA Testing Methodology: HPV DNA testing is typically performed on a sample taken from the cervix during a Pap smear or through a specific HPV test. It is not a blood test. If you suspect you have been exposed to HPV or are experiencing symptoms, it is advisable to get tested as soon as possible. The timing of testing can vary; if you have had a recent exposure, waiting about three months is often recommended to allow for accurate results.

In summary, HPV is a common virus that can lead to various health issues, including genital warts and cancers. While many infections resolve on their own, regular monitoring and communication with your healthcare provider are crucial for managing your health. If you have concerns about HPV or its implications for your sexual health, consider discussing them with a healthcare professional who can provide personalized advice and support.

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