Essential Tremor: Causes, Treatments, and Next Steps - Neurology

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Tremors in the hands, feet, and body?


Hello, doctor: I would like to ask about my condition.
I noticed that my left hand has been trembling since high school, and now my right hand also has slight tremors.
When I extend my five fingers forward, they tremble significantly.
When I try to grasp something, my fingers shake, and even my toes tremble when I exert myself to bend them.
When I stretch my legs out straight while in the air, they also shake, and my body trembles as well.
Even when I lie in bed and slowly bend forward to get up, I notice trembling from my abdomen to my cheeks, which my family has also observed.
I feel that it does not affect my daily life, but I am concerned it might worsen, so I went to a hospital to see a neurologist.
I underwent an EEG and thyroid blood tests, which showed no abnormalities.
The doctor said I am too young to have Parkinson's disease and diagnosed me with essential tremor.
I was prescribed the following medications: propranolol 10 mg, trihexyphenidyl 2 mg, deanxit 10 mg, and clonazepam 0.5 mg.
However, I feel that these medications do not seem to help with the tremors; I only notice that propranolol slows my heart rate.
Recently, during a health check-up, I found out that my hemoglobin is below the standard, my triglycerides are low, and I often experience orthostatic hypotension.
I have been trying to improve my condition through daily jogging and dietary changes, but the tremors persist.
I would like to ask the doctor if the lack of effectiveness from these medications (I have read online that most people experience improvement with propranolol, but I have not) still indicates essential tremor? How can I improve my condition? Should I undergo further examinations?

rlh, 20~29 year old female. Ask Date: 2017/09/19

Dr. Jiang Junyi reply Neurology


Hello, essential tremor: The exact cause of the tremor cannot be determined; it may be due to a specific constitution or hereditary tremor.
Typically, the tremor is more pronounced when holding objects, while some individuals may experience shaking when writing or performing specific actions.
Generally, propranolol is quite effective, although some individuals may not tolerate the side effects well.
I recommend using a small dose multiple times a day, such as half a tablet four times daily.
Some patients may also respond to Gabapentin or Topiramate, which can help reduce the frequency of tremors.
I suggest discussing treatment options with your attending physician.
Wishing you good health, peace, and happiness.
Dr.
Tao cares about you.

Reply Date: 2017/09/19

More Info


Essential tremor (ET) is a neurological disorder characterized by involuntary, rhythmic shaking, most commonly affecting the hands, but it can also impact the head, voice, and other parts of the body. Understanding the causes, treatments, and next steps for managing essential tremor is crucial for those affected by this condition.


Causes of Essential Tremor
The exact cause of essential tremor is not fully understood, but it is believed to be related to genetic factors, as it often runs in families. It is classified as a movement disorder and is distinct from other tremors, such as those associated with Parkinson's disease. In many cases, essential tremor can be exacerbated by stress, fatigue, caffeine, and certain medications. Unlike Parkinson's, essential tremor typically does not lead to other neurological symptoms, which can help differentiate it during diagnosis.


Symptoms
The primary symptom of essential tremor is shaking, which can vary in severity. Patients may notice tremors when performing tasks that require fine motor skills, such as writing, eating, or using tools. In your case, you mentioned that both hands tremble, especially when extending your fingers or performing physical activities. This can be frustrating and may lead to difficulties in daily activities, although you noted that it does not significantly impact your life at this time.


Diagnosis
Diagnosis of essential tremor typically involves a thorough clinical evaluation, including a detailed medical history and neurological examination. Tests such as blood tests and imaging studies (like MRI) may be conducted to rule out other conditions. Since you have already undergone tests like EEG and thyroid function tests, and your doctor has ruled out Parkinson's disease, it seems likely that your symptoms align with essential tremor.


Treatment Options
Treatment for essential tremor can vary based on the severity of symptoms and their impact on daily life. Common treatment options include:
1. Medications:
- Propranolol: A beta-blocker that is often effective in reducing tremors. However, as you've experienced, not everyone responds to it.
- Primidone: An anticonvulsant that can also help reduce tremors.

- Trihexyphenidyl: An anticholinergic medication that may help, but it is more commonly used for Parkinson's disease.

- Clonazepam: A benzodiazepine that can help with anxiety and may reduce tremors in some cases.

- If you find that these medications are not effective, it may be worth discussing alternative medications with your doctor.

2. Lifestyle Modifications:
- Reducing caffeine intake, managing stress, and ensuring adequate rest can help minimize tremors.

- Regular exercise, like jogging, can improve overall health and may help with symptoms.

3. Therapies:
- Occupational therapy can provide strategies to cope with tremors in daily activities.

- Physical therapy may help improve muscle control and coordination.

4. Surgical Options:
- In severe cases where tremors significantly impair quality of life and are unresponsive to medication, surgical options such as deep brain stimulation (DBS) may be considered.


Next Steps
Given that you are experiencing persistent tremors despite medication, it is advisable to follow up with your neurologist. They may consider adjusting your medication regimen or exploring other treatment options. Additionally, further evaluations might be necessary to ensure that there are no underlying conditions contributing to your symptoms.

In summary, while essential tremor can be challenging, many treatment options are available. It is essential to work closely with your healthcare provider to find the most effective management strategy tailored to your needs. Regular follow-ups and open communication about your symptoms and treatment responses will be key in managing this condition effectively.

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