Managing Side Effects of Glucophage for PCOS: Dizziness and Nausea Concerns - Obstetrics and Gynecology

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After taking menstrual regulation medication, symptoms such as dizziness, lightheadedness, nausea, vomiting, and drowsiness have occurred?


Hello: Due to polycystic ovary syndrome, a physician prescribed Glucophage as a medication to regulate menstruation and improve endocrine function.
However, since the first day of taking it, I have experienced symptoms such as dizziness, lightheadedness, drowsiness, and nausea.
I understand that nausea and vomiting are normal side effects.
I would like to know if drowsiness and dizziness/lightheadedness are adverse reactions.
Should I discontinue the medication? If I am feeling very uncomfortable over the next couple of days, should I go to the emergency room or wait until my follow-up appointment in a month to adjust the medication? Additionally, are the drowsiness and dizziness caused by Glucophage, or could there be other underlying issues? Which specialty should I consult for further examination? Thank you.

Xiao Mei, 10~19 year old female. Ask Date: 2017/09/22

Dr. Huang Jianzhong reply Obstetrics and Gynecology


Polycystic ovary syndrome (PCOS) is a condition for which a physician prescribed Glucophage (metformin) to regulate menstruation and improve endocrine function.
However, from the first day of taking the medication, symptoms such as dizziness, lightheadedness, drowsiness, and nausea have occurred.
I understand that nausea is a common side effect.

1.
I would like to know if drowsiness, dizziness, and lightheadedness are adverse reactions.
Should I discontinue the medication?
Answer: These may be adverse reactions; it is advisable to discontinue the medication.
2.
If I am feeling very uncomfortable over the next two days, should I go to the emergency room or wait until my follow-up appointment in a month to adjust my medication?
Answer: It is better to go to the emergency room.
3.
Are the drowsiness and dizziness caused by Glucophage, or could there be other underlying issues? Which specialty should I consult for further examination?
Answer: You should consult a family medicine physician.

Reply Date: 2017/09/22

More Info


Managing the side effects of Glucophage (metformin) for Polycystic Ovary Syndrome (PCOS) can be challenging, especially when experiencing symptoms like dizziness, nausea, and drowsiness. It’s important to understand both the common side effects of the medication and the potential need for further evaluation of your symptoms.


Understanding Glucophage and Its Side Effects
Glucophage is commonly prescribed for managing insulin resistance in patients with PCOS. While it is effective in regulating menstrual cycles and improving metabolic parameters, it can also lead to gastrointestinal side effects. The most frequently reported side effects include nausea, vomiting, diarrhea, and abdominal discomfort. These symptoms are often due to the medication's effect on the gastrointestinal tract and can sometimes be mitigated by taking the medication with food or starting with a lower dose and gradually increasing it.

However, symptoms such as dizziness, drowsiness, and lightheadedness are less common and may not be directly related to Glucophage. Dizziness can be a result of several factors, including dehydration, low blood sugar (hypoglycemia), or even anxiety. Drowsiness could be linked to other underlying conditions or medications you may be taking.

When to Seek Medical Attention
If you are experiencing significant discomfort, such as persistent dizziness and drowsiness, it is crucial to consult with your healthcare provider. You should not stop taking Glucophage abruptly without medical advice, as this could lead to a rebound effect on your blood sugar levels. Instead, consider the following steps:
1. Contact Your Healthcare Provider: Before making any changes to your medication regimen, reach out to your prescribing physician. They may suggest adjusting your dosage or switching to a different medication if the side effects are intolerable.

2. Monitor Your Symptoms: Keep a detailed record of your symptoms, including when they occur, their severity, and any other factors that might be contributing (like diet, hydration, or stress levels). This information can help your doctor make a more informed decision.

3. Consider an Urgent Visit: If your symptoms worsen or you experience severe dizziness that affects your ability to function, it may be wise to visit an urgent care center or emergency department. They can assess whether your symptoms are related to Glucophage or if there is another underlying issue that needs to be addressed.


Potential Underlying Issues
Given that dizziness and drowsiness can stem from various causes, it may be beneficial to undergo a comprehensive evaluation. You might consider seeing a primary care physician or an endocrinologist, who can assess your overall health, including blood sugar levels, thyroid function, and other hormonal balances.

Conclusion
In summary, while nausea and gastrointestinal discomfort are common side effects of Glucophage, dizziness and drowsiness warrant further investigation. It is essential to communicate openly with your healthcare provider about your symptoms and concerns. They can help determine whether these side effects are related to the medication or if there are other health issues at play. Always prioritize your health and safety by seeking professional guidance when experiencing adverse effects from any medication.

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