Asthma Medications: Nail Changes and Muscle Cramps Explained - Family Medicine

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Asthma medication, nails, muscle cramps?


The doctor diagnosed me with asthma, and I usually use Duasmas HFA 200 twice in the morning and evening, along with allergy medication and Hexoline.
However, I've noticed that over the past few months, two of my fingernails have developed straight brown lines.
Is the area between the nail and the flesh of the finger called the nail bed? There are also one or two small black dots appearing around the outer edge of the junction, which I have clipped or picked off, and while they disappear, they reappear after a while.
Additionally, small flesh-like growths have been forming around the outer edge of the nail bed.
Since they are under the nail, they are not a concern, but once I cut my nail too short, and while doing activities, I rubbed against the growth, which was painful and occasionally bled.
I mentioned this to the doctor, but he didn't say anything about it and only focused on what he wanted to discuss.
I initially thought stopping the medication would resolve the issue, and while I noticed no new growths, the black dots have recently increased, and I clipped them again.
I wanted to take a photo, but the growths are too small to capture, although they are clearly visible to the naked eye.

(1) What could this phenomenon be?
(2) If I notice any abnormalities in the future, should I see a dermatologist?
(3) I suddenly thought, could using asthma medication lead to cramps and drooling? I never had cramps before, but now I sometimes experience them while sleeping, and once or twice while sitting, the cramps occur.
Interestingly, when sleeping, it's my left leg, and when sitting, it's my right leg that cramps.
Thank you.

Niming, 20~29 year old female. Ask Date: 2017/09/25

Dr. Liao Yaopan reply Family Medicine


Hello, regarding these questions:
1.
It is advisable to have a dermatologist evaluate the condition of your finger skin in person.
2.
"After using asthma medication, is it common to experience cramps and excessive salivation?" - Clinically, we do not encounter many patients with similar reactions; it is still recommended to consult your prescribing physician.
3.
There are several issues to clarify regarding the problem of cramps.
Please note: online consultations are not equivalent to in-person medical visits and cannot provide accurate diagnoses or treatment recommendations.
Changhua Hospital cares about you.

Reply Date: 2017/09/25

More Info


Understanding the potential side effects and interactions of asthma medications, particularly those you mentioned—Duasma HFA (a combination of albuterol and ipratropium), antihistamines, and Hexaline (a bronchodilator)—is crucial for managing your condition effectively.
1. Nail Changes: The appearance of brown lines on your nails, known as "splinter hemorrhages," can be indicative of various underlying conditions, including trauma, infections, or systemic diseases. The small black dots you described at the nail bed could be a result of minor bleeding or even fungal infections. The growth of small flesh-like bumps (which you referred to as "肉芽") around the nail area could be a condition known as pyogenic granuloma, which is often benign but can be uncomfortable, especially if it gets irritated.
It is important to note that while these changes can be alarming, they are not commonly associated with asthma medications. However, if you have been using these medications frequently, any changes in your body should be monitored closely. If the changes persist or worsen, it would be prudent to consult a dermatologist who specializes in skin and nail conditions.
2. Consulting a Specialist: Given the symptoms you described, including the changes in your nails and the growth of small bumps, a visit to a dermatologist would be advisable. They can provide a thorough examination and may perform tests to rule out any underlying conditions. If you notice any additional symptoms such as pain, swelling, or changes in color, these should be reported to your healthcare provider immediately.

3. Muscle Cramps and Salivation: Regarding your concerns about muscle cramps and increased salivation after using asthma medications, it is essential to understand that certain bronchodilators can lead to side effects such as muscle cramps. This is particularly true if the medications lead to electrolyte imbalances or if they stimulate the nervous system excessively.
Albuterol, for instance, can cause muscle tremors and cramps in some individuals, especially if used in higher doses or more frequently than prescribed. Increased salivation is less common but can occur as a side effect of some medications, particularly those that affect the autonomic nervous system.
If you are experiencing cramps, it may be beneficial to ensure you are adequately hydrated and consider your electrolyte intake, as imbalances can contribute to muscle cramping. If these symptoms persist, you should discuss them with your healthcare provider, who may consider adjusting your medication or exploring other underlying causes.

In summary, while the changes in your nails and the occurrence of muscle cramps are concerning, they are not typical side effects of asthma medications. It is crucial to monitor these symptoms and consult with appropriate specialists to ensure your overall health and well-being. Always communicate openly with your healthcare provider about any new symptoms or concerns, as they can help you navigate your treatment plan effectively.

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