Trigeminal Neuralgia Symptoms and Treatment Options - Neurology

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Trigeminal nerve symptoms


Doctor, two months ago I experienced a dull pain in the area of the second-to-last tooth on the upper left side.
I also felt numbness and a throbbing sensation from the lower left corner of my left eye to my left temple.
However, the pain was not severe.
Initially, the symptoms occurred 5-6 times a day, lasting a few minutes each time.
I didn't pay much attention to it, and now the symptoms have decreased to 1-2 times a day.
I have had my teeth checked, and the dentist said there were no issues.
I also underwent a brain MRI, which reported no abnormalities.
I would like to know if this could be a problem with the trigeminal nerve.
My family doctor prescribed Gabapentin 100 mg; is it safe to take?

James, 30~39 year old female. Ask Date: 2017/10/07

Dr. Jiang Junyi reply Neurology


Hello, based on your description, it seems more like trigeminal neuralgia affecting the second branch of the trigeminal nerve.
There are many causes of trigeminal neuralgia, with approximately 80% attributed to compression of the trigeminal nerve by vascular structures as it exits the brainstem.
Other causes, such as vestibular schwannoma, meningioma, multiple sclerosis, and herpes zoster, can lead to demyelination of the trigeminal nerve, altering its transmission of sensory signals.
This results in normal sensations like touch and temperature being amplified into pain signals, subsequently triggering the symptoms of trigeminal neuralgia.
In terms of treatment: unlike other types of pain, anti-inflammatory and analgesic medications are not very effective for trigeminal neuralgia.
The primary treatment for trigeminal neuralgia involves anticonvulsant medications, with the most commonly used being carbamazepine (Tegretol), oxcarbazepine (Trileptal), and lamotrigine.
These anticonvulsants have been proven effective in treatment, making pharmacotherapy the first-line option.
However, it is important to note that these medications should be used according to a physician's instructions.
Anticonvulsants are not pain relievers and should not be adjusted based on the severity of the patient's condition.
They should be started at a low dose as recommended by the physician and increased gradually to minimize dizziness as a side effect.
Gabapentin, which you mentioned, can also be considered a second-line medication.
The course of trigeminal neuralgia varies from person to person.
Episodes can last from a few days to several weeks or months, followed by periods of remission.
Symptoms can recur easily, but effective treatment can usually control them.
I recommend discussing your condition and treatment options with a neurologist.
Wishing you good health and peace.

Reply Date: 2017/10/07

More Info


Trigeminal neuralgia (TN) is a chronic pain condition that affects the trigeminal nerve, which is responsible for sensation in the face. It is characterized by episodes of severe, shooting pain that can be triggered by everyday activities such as chewing, speaking, or even touching the face. Your symptoms, including the dull pain in the upper left teeth area and the sensation of numbness and pressure extending to the left eye and temple, could indeed suggest the presence of trigeminal neuralgia, especially since dental evaluations and MRI scans have ruled out other potential causes.

The frequency and intensity of your symptoms, starting at 5-6 times a day and now reduced to 1-2 times, can be typical of TN, where pain episodes can fluctuate. The fact that the pain is not severe at this moment does not rule out the possibility of TN, as the condition can vary significantly in its presentation.

Gabapentin, which you mentioned was prescribed by your family doctor, is commonly used to treat neuropathic pain, including trigeminal neuralgia. It works by stabilizing electrical activity in the brain and affecting the way nerves send messages to your brain. Gabapentin is generally well-tolerated, but like any medication, it can have side effects. Common side effects include dizziness, fatigue, and drowsiness. It is important to start with a low dose and gradually increase it as needed, under the guidance of your healthcare provider.

In terms of treatment options for trigeminal neuralgia, there are several approaches:
1. Medications: Besides gabapentin, other medications such as carbamazepine (Tegretol) and oxcarbazepine (Trileptal) are often first-line treatments for TN. These medications can help reduce the frequency and severity of pain episodes.

2. Surgical Options: If medications are ineffective or cause intolerable side effects, surgical options may be considered. Procedures such as microvascular decompression aim to relieve pressure on the trigeminal nerve, while other techniques like radiofrequency rhizotomy can disrupt pain transmission.

3. Alternative Therapies: Some patients find relief through alternative therapies such as acupuncture, biofeedback, or physical therapy. While these may not work for everyone, they can be part of a comprehensive pain management strategy.

4. Lifestyle Modifications: Identifying and avoiding triggers can also help manage symptoms. Keeping a pain diary to track when episodes occur can be beneficial in recognizing patterns and triggers.

It’s crucial to maintain open communication with your healthcare provider about your symptoms and treatment response. If gabapentin is effective in managing your pain, it may be a suitable long-term option. However, if you experience side effects or if your symptoms worsen, further evaluation and adjustment of your treatment plan may be necessary.

In summary, your symptoms could indeed indicate trigeminal neuralgia, and gabapentin is a reasonable medication to consider. Always consult with your healthcare provider before starting or adjusting any medication, and ensure that you have a comprehensive treatment plan tailored to your specific needs.

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