Pelvic Inflammatory Disease and Medication Guidance - Obstetrics and Gynecology

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Pelvic Inflammatory Disease and Medication Consultation


Hello Doctor, I have been experiencing recurrent vaginal infections and have been consistently following up with my physician.
I have been taking medications and using suppositories.
Recently, I have noticed some abdominal discomfort and lower back pain when bending over.
On October 6, I visited a gynecologist for an examination, which included a pelvic exam and palpation.
The doctor diagnosed me with pelvic inflammatory disease (PID) and prescribed a five-day course of metronidazole and ciprofloxacin.
However, by October 10, I have not noticed any improvement; my symptoms remain the same, and my lower back still hurts.
Can both of these medications effectively treat pelvic inflammatory disease? I am concerned about the potential for antibiotic resistance.
Should I complete the five-day course and then return for a follow-up, or should I go back to the doctor now to discuss my ongoing symptoms? Which option would be better? Thank you, Doctor.

Niming, 20~29 year old female. Ask Date: 2017/10/10

Dr. Huang Jianzhong reply Obstetrics and Gynecology


I have been experiencing recurrent vaginal infections and have been consistently visiting the doctor, taking medications and using suppositories.
Recently, I have noticed some abdominal discomfort and lower back pain when bending over.
On October 6, I visited a gynecologist for an examination, which included a pelvic exam and palpation.
The doctor diagnosed me with pelvic inflammatory disease and prescribed a five-day course of metronidazole and ciprofloxacin.
However, by October 10, I felt no improvement, and my symptoms remained the same, with persistent lower back pain.

Can both of these medications effectively treat pelvic inflammatory disease? I am concerned about the potential for antibiotic resistance.
Should I complete the five-day course and return for a follow-up, or should I go back to the doctor immediately to discuss my ongoing symptoms?
Answer: Both metronidazole and doxycycline or ciprofloxacin can be used to treat pelvic inflammatory disease.
Typically, a course of treatment lasts 7-10 days or even 10-14 days.
If the diagnosis is correct, you should see some improvement.
If your symptoms remain unchanged and you continue to experience lower back pain, it is advisable to consult a family physician or an orthopedic specialist.

Reply Date: 2017/10/10

More Info


Pelvic Inflammatory Disease (PID) is a serious infection of the female reproductive organs, often caused by sexually transmitted infections (STIs) like chlamydia and gonorrhea, but it can also result from other infections. PID can lead to severe complications, including chronic pelvic pain, infertility, and ectopic pregnancy if not treated promptly and effectively.
In your case, you have been diagnosed with PID and prescribed metronidazole and ciprofloxacin. Both of these antibiotics are commonly used to treat PID. Metronidazole is effective against anaerobic bacteria and certain protozoa, while ciprofloxacin is a fluoroquinolone antibiotic that targets a broad range of bacteria, including those that may cause STIs. The combination of these two medications is often chosen to cover a wide spectrum of potential pathogens involved in PID.

However, it is concerning that you have not noticed any improvement in your symptoms after completing the five-day course of antibiotics. Persistent symptoms such as abdominal and lower back pain may indicate that the infection is not fully resolved or that there may be other underlying issues contributing to your discomfort.
Regarding your concern about antibiotic resistance, it is crucial to use antibiotics judiciously. If you have completed the prescribed course and still experience symptoms, it is essential to return to your healthcare provider for further evaluation. Do not wait until the end of the course if your symptoms are severe or worsening. Your doctor may need to reassess your condition, possibly perform additional tests, or consider alternative treatments.

In some cases, PID may require a longer duration of antibiotic therapy or a different combination of medications, especially if there is a suspicion of a more resistant infection or if complications such as abscess formation are present. Additionally, if you have a history of recurrent vaginal infections, it might be worth discussing with your doctor the possibility of further investigations to identify any underlying conditions that may predispose you to these infections.

It's also important to consider lifestyle factors that may contribute to your symptoms. Stress, lack of sleep, and poor nutrition can all impact your immune system and overall health, potentially making it harder for your body to fight off infections.
In summary, while metronidazole and ciprofloxacin are appropriate for treating PID, your lack of improvement warrants a follow-up with your healthcare provider. They may need to adjust your treatment plan based on your current symptoms and any new findings. Always prioritize open communication with your healthcare provider about your symptoms and concerns, as this will help ensure you receive the most effective care.

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