Questions About Oral Medications for Toenail Fungus Treatment - Dermatology

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Questions regarding oral medications for onychomycosis?


Hello doctor, I have been experiencing symptoms of onychomycosis (fungal nail infection) on my toes for over a year.
Recently, I started seeing a dermatologist for treatment.
Initially, I received medication in central Taiwan and took Terbinafine Fungitech for 6 weeks.
Later, due to certain reasons, I returned to southern Taiwan for work and consulted a doctor near my home.
The doctor was very kind and prescribed Lamisil tablets.
I would like to know if this will affect my treatment.
Thank you.

Wuming Shi, 30~39 year old female. Ask Date: 2017/10/14

Dr. Wu Yuxin reply Dermatology


These two medications contain the same active ingredient; they are just produced by different manufacturers.

Reply Date: 2017/10/14

More Info


When it comes to treating toenail fungus, particularly with oral medications like Terbinafine (often marketed under the brand name Lamisil), it's important to understand how these medications work and the implications of switching between different formulations or brands.

Terbinafine is an antifungal medication that is effective against a variety of fungal infections, including onychomycosis (fungal nail infections). It works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes, which ultimately leads to the death of the fungus. The treatment duration for toenail fungus can vary, but it typically lasts from 6 weeks to several months, depending on the severity of the infection and the specific medication used.

In your case, you mentioned that you initially took Terbinafine for 6 weeks and then switched to Lamisil tablets. It's important to note that Lamisil is simply a brand name for Terbinafine, so the active ingredient remains the same. Therefore, switching from one brand to another should not significantly impact your treatment, as long as the dosage and duration remain consistent with what your healthcare provider has recommended.

However, there are a few considerations to keep in mind:
1. Consistency in Treatment: It is crucial to adhere to the prescribed treatment regimen. If your new doctor has recommended continuing with Lamisil tablets, ensure that you follow their instructions regarding dosage and duration. Consistency is key in effectively treating fungal infections.

2. Monitoring for Side Effects: Both Terbinafine and Lamisil can have side effects, including gastrointestinal issues, liver function abnormalities, and skin reactions. It's important to monitor your health and report any unusual symptoms to your healthcare provider. Regular liver function tests may be recommended during treatment, especially if you have any pre-existing liver conditions.

3. Completing the Full Course: Even if you start to see improvement in your symptoms, it is essential to complete the full course of treatment as prescribed. Stopping the medication prematurely can lead to a recurrence of the infection, as not all fungal cells may be eradicated.

4. Follow-up Appointments: Regular follow-ups with your healthcare provider are important to assess the effectiveness of the treatment and make any necessary adjustments. If you notice any worsening of symptoms or new symptoms arise, do not hesitate to reach out to your doctor.

5. Potential Drug Interactions: If you are taking other medications, be sure to inform your healthcare provider, as there may be potential interactions that could affect the efficacy of the treatment or increase the risk of side effects.

In summary, switching from Terbinafine to Lamisil should not negatively impact your treatment, as they contain the same active ingredient. However, it is crucial to follow your healthcare provider's instructions, complete the full course of treatment, and monitor for any side effects. If you have any concerns or experience any new symptoms, be sure to communicate with your healthcare provider for further guidance.

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