Can Sperm Be Retrieved from Testes if Epididymis is Absent? - Urology

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Testicular sperm extraction (TESE)


If the epididymis is absent but the testicles are normal, is it possible to retrieve sperm from the testicles?

Zhe, 10~19 year old female. Ask Date: 2017/10/19

Dr. Du Shixi reply Urology


Hello: Sperm can be retrieved from the testicles, but it is not always successful every time.
Additionally, it is an out-of-pocket expense and can be quite costly.
Wishing you good health.

Reply Date: 2017/10/19

More Info


The question of whether sperm can be retrieved from the testes in the absence of the epididymis is a complex one that touches on various aspects of male reproductive health and assisted reproductive technologies.
To begin with, the epididymis is a crucial structure in the male reproductive system, responsible for the maturation, storage, and transport of sperm. It is located behind the testes and connects the testes to the vas deferens. If the epididymis is absent, which can occur due to congenital conditions (like congenital absence of the vas deferens) or surgical removal, it raises questions about sperm retrieval and fertility.

In cases where the epididymis is absent but the testes are functioning normally, it is indeed possible to retrieve sperm directly from the testes. This procedure is known as Testicular Sperm Extraction (TESE). TESE involves surgically removing a small amount of testicular tissue, from which sperm can be isolated. This technique is particularly useful for men who have obstructive azoospermia, where sperm production is normal, but there is a blockage preventing sperm from reaching the ejaculate.

The success of TESE largely depends on the underlying condition causing the absence of the epididymis. If the testes are producing viable sperm, even in the absence of the epididymis, there is a good chance that sperm can be retrieved. The retrieved sperm can then be used for various assisted reproductive technologies, such as Intra-Cytoplasmic Sperm Injection (ICSI), where a single sperm is injected directly into an egg to facilitate fertilization.

It's important to note that the retrieval process may vary in complexity and success rates. Factors such as the age of the patient, the health of the testes, and the presence of any additional reproductive health issues can influence outcomes. Additionally, the surgical procedure itself carries risks, including bleeding, infection, and potential damage to surrounding tissues.

For men considering this option, a thorough evaluation by a urologist or a reproductive endocrinologist is essential. They can perform tests to assess sperm production and guide the patient through the process, including discussing the potential for successful retrieval and the implications for fertility.

In conclusion, while the absence of the epididymis presents challenges, sperm can still be retrieved from the testes if they are functioning normally. Advances in reproductive technology have made it possible for men with such conditions to achieve biological fatherhood, even when traditional pathways to sperm delivery are obstructed. If you or someone you know is facing this situation, consulting with a specialist in male fertility can provide valuable insights and options tailored to individual circumstances.

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