Blood Test Results: Key Indicators for Lymphoma Concerns - Oncology

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Blood test


Hello Doctor: I have had swollen lymph nodes in my neck for some time, so I went for a blood test.
I would like to ask about the significance or implications of the following values: 1.
Lymphocytes: 15.6 (normal range: 19.0-48.0) 2.
Hemoglobin: 11 (normal range: 11.3-15.3) 3.
Platelets: 472 (normal range: 150-400)

Lin Ting, 10~19 year old female. Ask Date: 2017/10/31

Dr. Hu Ziren reply Oncology


Initially, there appears to be anemia and thrombocytosis.

Reply Date: 2017/10/31

More Info


When interpreting blood test results, especially in the context of potential lymphoma or other hematological concerns, it is crucial to understand the significance of each parameter and how they relate to overall health. In your case, you provided three key indicators: lymphocyte count, hemoglobin level, and platelet count. Let's break down each of these components and their implications.

1. Lymphocyte Count (15.6, Normal Range: 19.0-48.0):
Lymphocytes are a type of white blood cell that play a vital role in the immune system, particularly in fighting infections and in the body's response to cancer. A lymphocyte count below the normal range can indicate several conditions. It may suggest an ongoing infection, as the body may be utilizing lymphocytes to combat pathogens. Additionally, low lymphocyte counts can be associated with bone marrow disorders, autoimmune diseases, or the effects of certain medications. In the context of lymphoma, a low lymphocyte count can be concerning, but it is not definitive on its own. Further evaluation, including imaging studies and possibly a lymph node biopsy, may be warranted to assess for malignancy.

2. Hemoglobin Level (11, Normal Range: 11.3-15.3):
Hemoglobin is the protein in red blood cells responsible for transporting oxygen throughout the body. A hemoglobin level below the normal range indicates anemia, which can result from various causes, including nutritional deficiencies (such as iron, vitamin B12, or folate), chronic diseases, or bone marrow problems. Anemia can lead to fatigue, weakness, and other systemic symptoms. In the context of lymphoma, anemia can occur due to the disease itself or as a result of treatment. It is essential to investigate the cause of anemia, as it may provide additional clues about your overall health and potential underlying conditions.

3. Platelet Count (472, Normal Range: 150-400):
Platelets are crucial for blood clotting. An elevated platelet count, known as thrombocytosis, can occur for several reasons, including inflammation, infection, or as a reactive process to other conditions, such as anemia or malignancy. In some cases, elevated platelets can be associated with myeloproliferative disorders, which are conditions where the bone marrow produces too many blood cells. While a high platelet count alone is not diagnostic of lymphoma, it can be part of a broader picture that requires further investigation.


Conclusion and Next Steps:
Given your symptoms of neck lymphadenopathy (swollen lymph nodes) and the blood test results, it is essential to follow up with your healthcare provider for a comprehensive evaluation. They may recommend additional tests, such as imaging studies (like a CT scan) or a biopsy of the lymph nodes, to determine the cause of the lymphadenopathy and assess for lymphoma or other conditions.
It's also important to consider your overall clinical picture, including any additional symptoms you may be experiencing, such as weight loss, night sweats, or fever, which can be associated with lymphoma.
In summary, while your blood test results show some abnormalities, they do not definitively indicate lymphoma. A thorough evaluation by a healthcare professional, including a detailed history, physical examination, and possibly further testing, is necessary to arrive at an accurate diagnosis and appropriate management plan.

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