Persistent Itching: Seeking Solutions Beyond Dermatology - Dermatology

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Widespread itching that doesn't subside with medication?


Hello, doctor.
I have been experiencing intermittent itching all over my body from the age of 13 to now, at 24 years old, especially severe before bedtime, which significantly affects my sleep.
I visited a clinic, and they diagnosed me with atopic dermatitis.
I have been under treatment for over a year, and the medications have been adjusted many times without alleviating the itching sensation (I have asked, and the current medication is the strongest, containing two types of steroids).
I went to the dermatology department at Wuchi Tzongzhong and had blood tests done, which showed no issues.
The medications prescribed have had no effect.
I also consulted the Rheumatology and Immunology department at China Medical University, where blood tests indicated that I am allergic to dust mites.
The medications prescribed were ineffective, and I have followed their advice on managing dust mite issues without improvement.
I have also seen several traditional Chinese medicine practitioners who suggested that I have liver problems, but after several years of treatment, there has been no change.
During episodes of itching, there are no rashes or red spots; my skin appears normal.
I would like to ask the doctor if I should consider consulting a different specialty or if there are any more reputable dermatology experts I could see.

Mr. Chen, 20~29 year old female. Ask Date: 2017/11/08

Dr. Wu Yuxin reply Dermatology


Without actually seeing the lesion, it is impossible to determine your issue.
If it is very concerning, you should seek medical attention.
A proper examination is necessary to understand the problem and to find a way to address it.

Reply Date: 2017/11/08

More Info


Persistent itching can be a frustrating and debilitating condition, especially when it affects your quality of life and sleep. Based on your description, it seems that you have been dealing with this issue for over a decade, and despite various treatments and consultations with dermatologists and other specialists, you have not found relief. This situation can be particularly challenging when the cause of the itching is not clear, and standard treatments have failed to provide the desired results.

From your account, it appears that you have been diagnosed with atopic dermatitis (eczema), which is a common skin condition characterized by dry, itchy skin. The fact that you have been prescribed potent topical steroids suggests that your condition is considered severe. However, the persistent nature of your itching, especially in the absence of visible skin changes like rashes or redness, raises the possibility of other underlying issues.

One potential consideration is that your itching could be related to a systemic condition rather than a purely dermatological one. Conditions such as allergies, autoimmune disorders, or even psychological factors can manifest as itching without accompanying skin lesions. Since you mentioned that you have been tested for dust mite allergies and have taken measures to manage this issue without improvement, it may be worthwhile to explore other potential allergens or irritants in your environment, including food allergies or sensitivities.

Additionally, the fact that you have consulted with traditional Chinese medicine practitioners who suggested liver issues indicates that you might be exploring a holistic approach to your symptoms. While alternative medicine can provide some insights and relief for certain individuals, it is essential to ensure that any treatment you pursue is evidence-based and complements conventional medical care.

Given your ongoing symptoms and the lack of improvement with current treatments, it may be beneficial to seek a second opinion from a different dermatologist or a specialist in allergy and immunology. These professionals can conduct more comprehensive testing to identify potential triggers for your itching, including patch testing for contact dermatitis or further allergy testing.
Moreover, consider discussing with your healthcare provider the possibility of exploring treatments beyond topical steroids, such as systemic medications (like antihistamines, immunosuppressants, or biologics) that might be more effective for your condition. These options can help manage inflammation and reduce itching more effectively than topical treatments alone.

In terms of lifestyle modifications, maintaining a consistent skincare routine is crucial. Regularly applying moisturizers, avoiding harsh soaps, and taking lukewarm showers can help manage dryness and irritation. Additionally, implementing stress-reduction techniques such as mindfulness, yoga, or cognitive behavioral therapy may also provide relief, as stress can exacerbate itching.

In summary, while your persistent itching has been challenging to manage, it is essential to continue seeking answers and exploring different avenues of care. Consulting with specialists in dermatology and allergy, considering systemic treatments, and maintaining a diligent skincare routine can all contribute to improving your symptoms. Remember, you are not alone in this journey, and with persistence and the right approach, relief is possible.

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