Levonorgestrel Side Effects and Pregnancy Concerns - Obstetrics and Gynecology

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About ten days after taking levonorgestrel one week later?


I had sexual intercourse with my girlfriend on December 9th.
We used a condom, but it broke, and I also withdrew.
I took levonorgestrel the same day.
However, 11 days later, on December 19th, I experienced nausea, lower abdominal pain, and yellowish discharge.
Could these symptoms be side effects of levonorgestrel? Should I be concerned about the possibility of pregnancy?

Edison, 10~19 year old female. Ask Date: 2017/12/19

Dr. Cai Yonglong reply Obstetrics and Gynecology


It is normal to experience some spotting after taking emergency contraception.
However, if your next period is delayed, it is advisable to take a pregnancy test, as the effectiveness of emergency contraception is only about 85%.

Reply Date: 2017/12/19

More Info


Levonorgestrel is a synthetic progestin commonly used in emergency contraception, often referred to as the "morning-after pill." It is designed to prevent pregnancy after unprotected intercourse or contraceptive failure, such as a broken condom. Understanding the side effects and implications of taking Levonorgestrel, especially in the context of potential pregnancy, is crucial for anyone considering its use.

First, let's address the timing and mechanism of action of Levonorgestrel. It is most effective when taken within 72 hours after unprotected intercourse, but it can be taken up to 120 hours (5 days) after. The primary way it works is by delaying ovulation; if ovulation has already occurred, it may also prevent fertilization or implantation of a fertilized egg. However, if implantation has already taken place, Levonorgestrel is not effective in terminating an existing pregnancy.

Now, regarding the side effects you mentioned—nausea, abdominal pain, and changes in vaginal discharge—these can indeed be side effects of Levonorgestrel. Nausea is one of the most common side effects, affecting approximately 20% of women who take the medication. Abdominal pain or cramps can also occur, as the body reacts to the hormonal changes induced by the medication. The change in vaginal discharge, such as a yellowish or orange tint, could be related to hormonal fluctuations or even an indication of an infection, which should be evaluated by a healthcare provider.

As for the concern about pregnancy, if you took Levonorgestrel shortly after the condom broke, the likelihood of pregnancy is reduced, but not eliminated. The symptoms you are experiencing could be side effects of the medication rather than definitive signs of pregnancy. However, if your period is delayed or you experience other signs of pregnancy (such as breast tenderness, fatigue, or frequent urination), it would be prudent to take a home pregnancy test or consult with a healthcare provider for further evaluation.

In terms of pregnancy classification, Levonorgestrel is categorized as a Category X drug when used in the context of ongoing pregnancy, meaning it is contraindicated due to evidence of fetal harm. However, when used as directed for emergency contraception, it is not associated with an increased risk of birth defects or miscarriage if taken before pregnancy is established.

In summary, while Levonorgestrel can cause side effects such as nausea and abdominal discomfort, these do not necessarily indicate pregnancy. If you have concerns about the possibility of being pregnant or if your symptoms persist, it is advisable to consult a healthcare professional for personalized advice and potential follow-up testing. Always remember that while emergency contraception is a valuable option, it should not be used as a regular form of birth control, and discussing long-term contraceptive options with a healthcare provider is recommended for effective family planning.

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