the Worsening of Ulcerative Rectitis: Seeking Solutions - Surgery

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The exacerbation of ulcerative colitis..?


Hello Dr.
Ke,
I apologize for bothering you again with my questions (I previously inquired about #128682).
I was diagnosed with ulcerative colitis due to blood and mucus in my stool, with an inflammation level of 1.5 (on a scale where 3 is the highest), and the affected area measured 7-8 cm.
The doctor prescribed me Asacol (mesalamine) to take after each meal.
I have been diligent about taking my medication for the past three months.
During this time, the mucus has significantly decreased, but the amount of bleeding has not shown any noticeable improvement.
However, during my recent follow-up, I underwent a sigmoidoscopy, and the doctor informed me that my inflammation has worsened (increased to level 2), specifically concentrated in the rectal area without extending upward, leading to a diagnosis of ulcerative proctitis.
The doctor increased my Asacol dosage (4 tablets total: three meals and before bed) and also provided me with three enemas of Rowasa (mesalamine enema).
I would like to ask Dr.
Ke, why has my condition worsened despite my adherence to the medication? I have been maintaining a light diet, consuming plenty of fruits and vegetables, going to bed early, waking up early, and taking my medication on time.
This latest diagnosis has left me feeling very discouraged, and I am worried that this ulcerative proctitis may not be treatable.
What should I do? Should I consider seeking a second opinion at another hospital? (I am currently seeing a doctor at Shalu Kuang Tien Hospital, which has a rather poor reputation...)
I look forward to your response! Thank you!

Qiu Xiansheng, 20~29 year old female. Ask Date: 2017/12/21

Dr. Ke Fangxu reply Surgery


Ulcerative colitis is an autoimmune disease that requires long-term management, characterized by symptoms that can fluctuate between periods of remission and exacerbation.
Currently, you are receiving standard treatment; however, if your condition does not improve, it is advisable to consult a larger hospital and seek a referral to a rheumatologist for the prescription of immunosuppressive agents to prevent further deterioration of your symptoms.

Reply Date: 2017/12/21

More Info


Understanding the worsening of ulcerative rectitis can be quite distressing, especially when you are adhering to your treatment regimen and making lifestyle changes. It’s important to recognize that ulcerative colitis (UC), including its manifestation as ulcerative rectitis, can be a complex condition influenced by various factors, and sometimes, despite best efforts, symptoms may not improve as expected.

Firstly, it’s crucial to understand that ulcerative colitis is a chronic inflammatory bowel disease (IBD) characterized by inflammation of the colon and rectum. The severity of the disease can fluctuate, and patients may experience periods of remission followed by flare-ups. In your case, the increase in inflammation from grade 1.5 to grade 2 indicates a worsening of your condition, which can occur for several reasons, even with adherence to medication.

1. Medication Efficacy: While you have been taking Asacol (mesalamine), which is a 5-ASA (5-aminosalicylic acid) medication used to treat UC, it may not be sufficient for everyone. Some patients may require higher doses or additional medications, such as corticosteroids or immunosuppressants, to achieve better control of inflammation. The fact that your doctor has increased your dosage and added a rectal enema suggests that they are taking steps to intensify your treatment.

2. Diet and Lifestyle: Although you are eating a healthy diet rich in fruits and vegetables, individual responses to diet can vary significantly in IBD patients. Some foods may trigger symptoms or inflammation in certain individuals. Keeping a food diary to track what you eat and any symptoms that arise can help identify potential triggers. Additionally, stress management is crucial, as psychological stress can exacerbate symptoms of IBD.

3. Regular Monitoring: Regular follow-ups with your healthcare provider are essential. The fact that your doctor is monitoring your condition and adjusting your treatment plan is a positive sign. If you feel that your current treatment is not effective, discussing your concerns with your doctor is important. They may consider alternative therapies or refer you to a specialist in inflammatory bowel disease.

4. Second Opinions: If you have concerns about the quality of care you are receiving or feel that your treatment is not progressing as it should, seeking a second opinion can be beneficial. Different healthcare providers may have varying approaches to treatment, and a fresh perspective could provide new insights into managing your condition.

5. Psychological Support: Dealing with a chronic illness can be emotionally taxing. Consider seeking support from mental health professionals or support groups for individuals with IBD. Connecting with others who understand your experience can provide comfort and coping strategies.

In summary, while it is disheartening to see a worsening of your condition despite your efforts, it is important to remain proactive in your treatment. Communicate openly with your healthcare provider about your concerns, adhere to the prescribed treatment plan, and consider lifestyle modifications that may help. If necessary, don’t hesitate to seek a second opinion to explore all available options for managing your ulcerative rectitis effectively. Remember, managing IBD is often a journey that requires patience and persistence.

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