Tuberculosis Diagnosis and Treatment: Your Questions Answered - Pulmonology

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Diagnosis of pulmonary tuberculosis?


Hello, I submitted my first sputum sample for testing on October 27 (actually, I had no sputum, just saliva; should saliva not be used for testing if there is no sputum?).
I submitted samples again on October 31 and November 2.
The staining results showed that only the first sample had 1-2 /300 fields (scanty), while the subsequent samples were all negative.
The X-ray report from September indicated nonspecific mild exaggerated lung markings in both lungs, mild infiltration in the right lower lung field, and minimal degenerative changes in the thoracolumbar spine.
The December X-ray report showed no significant abnormalities in both lungs, mediastinum, heart, airway, diaphragm, and chest wall.
I started medication on November 2 and have been taking it until today, December 29.
The bacterial culture report has not yet come out.
The doctor has instructed me to continue taking five pills of the three-in-one medication and two pills of EMB, but the side effects are really uncomfortable.
How long do you generally need to take these medications? I heard that after two months of treatment, the dosage can be reduced; is that true? The doctor is reluctant to answer this part and just wants me to keep taking the medication.
Is this harmful to my body? Is it true that bacterial cultures take 6-8 weeks, but it has been much longer; what is the longest I should wait? Has there been any change in my X-ray results? Because it seems to look better from the wording, but the doctor says there has been no change.
He only instructed me to continue taking the medication and did not allow me to ask further questions.
The health authority is requesting a medical record review; I don’t know why the doctor is upset with me.
Under what circumstances is a medical record review necessary? Can my bacterial culture still be reviewed if it hasn’t come out yet? Can the results lead to a diagnosis? Can it affect the doctor’s diagnosis? How long do I have to wait after the review to get a formal answer? Due to poor communication with the doctor, can I change to see another doctor myself? Is it necessary to have the original attending physician's permission? Will other doctors in the same hospital accept me? I hope to receive treatment if I am sick and not take medication if I am not, as it is harmful to my body.
However, the doctor tends to want me to keep taking the medication without a clear timeline, which confuses me.
I apologize for asking so many questions, and thank you.

335, 50~59 year old female. Ask Date: 2017/12/29

Dr. Yang Wenda reply Pulmonology


Hello: We respect the physician's diagnosis and treatment regarding your condition.
If there is a case review, two experts will further validate your diagnosis.
Please do not worry! If you have difficulty communicating or asking questions to your attending physician, you may also consult other pulmonologists in the same hospital or obtain copies of your records to seek a second opinion at another hospital.

Reply Date: 2017/12/29

More Info


Diagnosing and treating tuberculosis (TB) can be a complex process, and your questions reflect the concerns many patients have when navigating this condition. Let's break down your inquiries and provide a comprehensive understanding of TB diagnosis and treatment.


1. Understanding Your Sputum Tests
You mentioned submitting sputum samples, but you were unsure if spitting saliva instead of actual sputum was appropriate. It's crucial to provide genuine sputum samples, as saliva may not contain the bacteria responsible for TB. Sputum should ideally come from deep within the lungs, which is why it's often recommended to produce samples first thing in the morning when mucus is more likely to be present. If you have difficulty producing sputum, you should discuss this with your healthcare provider, as they may suggest alternative methods, such as a bronchoscopy, to obtain a sample directly from your lungs.


2. Interpretation of X-ray Results
Your X-ray reports indicate some mild changes, but the December report shows no significant abnormalities. This could suggest that your lungs are stabilizing, but it's essential to correlate these findings with your clinical symptoms and sputum results. If your doctor believes there is no significant change, it may be because the changes are subtle and not clinically relevant at this time.


3. Duration of Treatment
Regarding your treatment regimen, TB typically requires a lengthy course of antibiotics, often lasting six months or longer. The initial phase usually involves a combination of medications (like the three-drug regimen you mentioned) for the first two months, followed by a continuation phase. After two months, if you are responding well and your sputum tests are negative, your doctor may consider adjusting your medication regimen. However, any changes should be made under medical supervision to ensure the effectiveness of the treatment and to prevent the development of drug-resistant TB.


4. Bacterial Culture Timing
You are correct that bacterial cultures can take 6-8 weeks to yield results, but in some cases, it may take longer. Factors such as the type of media used for culture and the specific characteristics of the bacteria can influence the time it takes to get results. If your culture results are delayed beyond the typical timeframe, it’s reasonable to follow up with your healthcare provider for clarification.


5. Medical Records Review
Regarding the review of your medical records by the health department, this typically occurs in cases where there is a need to ensure proper treatment protocols are being followed, especially in communicable diseases like TB. The review can happen even if culture results are pending, as it may involve assessing your treatment history and adherence to guidelines.

6. Changing Doctors
If you feel uncomfortable with your current physician's communication style or treatment plan, it is entirely within your rights to seek a second opinion. You do not necessarily need your current doctor’s permission to consult another physician, although it may be beneficial to inform them of your decision. Many hospitals have protocols for transferring care, and other doctors within the same institution may be willing to see you.


7. Concerns About Side Effects
It's understandable to be concerned about the side effects of TB medications. While these medications can have side effects, the benefits of treating TB generally outweigh the risks. If you are experiencing significant discomfort, you should communicate this to your healthcare provider. They may be able to adjust your treatment plan or provide supportive care to help manage side effects.


Conclusion
Navigating TB diagnosis and treatment can be daunting, especially with the uncertainty surrounding your sputum results and treatment duration. Open communication with your healthcare provider is essential. If you feel your concerns are not being adequately addressed, seeking a second opinion can provide you with the reassurance and clarity you need. Remember, effective treatment of TB is crucial not only for your health but also for public health, as TB is a contagious disease. Stay proactive in your care, and don't hesitate to advocate for yourself.

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