Depression Medication: Side Effects and Alternatives

Depression Medication Consultation

Hello Doctor: I was diagnosed with polycystic ovary syndrome (PCOS) in January last year and started taking Yaz to regulate my menstrual cycle in mid-February.
Around March last year, I began to experience feelings of depression and low mood.
I continued taking Yaz until early June, when I informed my gynecologist about my depressive symptoms, and the doctor switched my medication to Yasmin.
I have been taking Yasmin since early July, but my depressive symptoms worsened from early March, and after breaking up with my boyfriend in early October, my emotional instability increased.
I later visited a psychiatrist and was diagnosed with major depressive disorder.

In the first two weeks, the doctor prescribed me medications to take at bedtime, including Sustained-Release Mirtazapine and Venlafaxine Extended-Release Tablets.
After my mood stabilized slightly, the doctor changed my medications, but the number of medications increased.
Now, I take Wellbutrin after breakfast and dinner, Lexapro at bedtime, and 1/4 of a Seroquel Extended-Release Tablet.
My family is concerned about me taking so many medications due to potential side effects.
I understand that overcoming depression requires personal effort and should not rely solely on medication.
Initially, I took birth control pills to regulate my menstrual cycle, but I ended up developing depression.

I would like to ask the doctor about the potential side effects of the medications I am taking.
Can these medications lead to dependence if taken for a long time? Are there any methods to treat depression without medication? I am also worried about gaining weight, as I have already gained nearly 15 kilograms from taking Yasmin and Yaz, and changes in body shape are one of the reasons for my depression.

Zoe, 20~29 year old female. Ask Date: 2018/01/04

Dr. Qiu Junda reply Psychiatry

Hello.
If you are experiencing weight gain and worsening depression as side effects from taking birth control pills, it is advisable to discuss with your physician whether to discontinue the medication.
Regarding the psychiatric medications you are taking, antidepressants are generally considered to have a lower risk of addiction.
You can research their side effects, as some may indeed contribute to weight gain.
It is best to discuss this in detail with your psychiatrist, including non-pharmacological treatments for depression.
Additionally, you may want to look up information related to depression and stress management to learn some coping strategies, such as talking to friends or engaging in leisure activities, which may be beneficial.

Reply Date: 2018/01/04

More Info

When it comes to managing depression, particularly in the context of medication, there are several important considerations to keep in mind, especially regarding side effects and alternative treatments. Your situation, involving the transition from hormonal treatments to antidepressants, highlights the complexities of mental health management and the need for a tailored approach.

Firstly, it’s essential to understand that many medications prescribed for depression, such as SSRIs (Selective Serotonin Reuptake Inhibitors) and SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors), can have side effects. Common side effects include nausea, weight gain, fatigue, and sexual dysfunction. In your case, the concern about weight gain is particularly relevant, as some antidepressants can lead to significant changes in body weight. For instance, medications like Mirtazapine and certain SSRIs are known to be associated with weight gain. It’s crucial to discuss these concerns with your psychiatrist, as they can help you weigh the benefits of the medication against the side effects.

Regarding the potential for addiction, most antidepressants are not considered addictive in the traditional sense, but they can lead to dependence. This means that if you stop taking them suddenly, you might experience withdrawal symptoms. This is why it’s important to follow your doctor’s guidance on tapering off medication rather than stopping abruptly.

In terms of alternatives to medication, there are several effective strategies for managing depression that do not involve pharmaceuticals. Cognitive Behavioral Therapy (CBT) is one of the most researched and effective forms of psychotherapy for depression. It focuses on changing negative thought patterns and behaviors that contribute to depressive symptoms. Additionally, lifestyle changes such as regular physical activity, a balanced diet, and good sleep hygiene can significantly impact mood and overall mental health. Exercise, in particular, has been shown to release endorphins and improve mood, making it a valuable tool in managing depression.

Mindfulness and meditation practices can also be beneficial. These techniques help reduce stress and anxiety, which can exacerbate depressive symptoms. Engaging in social activities, pursuing hobbies, and maintaining connections with friends and family can provide emotional support and improve your mood.

If you are concerned about the side effects of your current medications, it’s important to have an open dialogue with your psychiatrist. They may consider adjusting your dosage, switching to a different medication with a more favorable side effect profile, or incorporating therapy into your treatment plan. It’s also worth exploring whether there are non-hormonal options for managing your polycystic ovary syndrome (PCOS) that might not contribute to your depressive symptoms.

In summary, managing depression effectively often requires a multifaceted approach that includes medication, therapy, lifestyle changes, and support systems. It’s vital to work closely with your healthcare provider to find the right balance that minimizes side effects while effectively addressing your mental health needs. Remember, you are not alone in this journey, and there are many resources and strategies available to help you navigate through your depression.

Similar Q&A

Managing Depression: Navigating Medication Side Effects and Care

My mother previously contracted Helicobacter pylori and was found to have a cyst in her gallbladder. Perhaps due to excessive worry, she developed depression and consulted a psychiatrist. Initially, her depression was manageable with medication. However, after some time, she bega...

Dr. Su Zongwei reply Psychiatry
Sometimes, it can be difficult to distinguish between physical symptoms of depression and side effects of medication, which requires careful adjustment of the medication. It is important to discuss with your physician whether to discontinue the medication, as stopping abruptly ma...

Long-Term Use of Antidepressants: Risks of Parkinson's Disease and Other Side Effects

Is long-term use of antidepressant medication associated with a higher risk of developing Parkinson's disease compared to the general population? Are there any other potential side effects?

Dr. Chen Guangpeng reply Psychiatry
Hello, Dudu online friend: Depression has become one of the top three major diseases of the 21st century. The development and market introduction of antidepressant medications have been rapidly evolving, ranging from tricyclic antidepressants (TCA), monoamine oxidase inhibitors (...

Understanding Remeron: Uses and Side Effects for Depression Treatment

I am currently suffering from severe depression. Previously, I experienced discomfort while taking medication - Paxil. My doctor has switched my medication, but I am unclear about the uses and side effects of the new medication (Remeron).

Dr. Gu Zhenting reply Pharmacology
Hello! Regarding Remeron: the generic name is Mirtazapine, which is an antidepressant used to treat major depressive disorder. This medication typically takes 1-2 weeks to start showing effects, and treatment should continue for 4-6 months after the patient has been completely fr...

Understanding SSRI Side Effects and Alternatives for Anxiety Management

Hello, Doctor. I have mild anxiety and panic symptoms, and I tend to be a nervous person, so I occasionally experience anxiety symptoms such as palpitations, dizziness, unexplained fear, numbness in my hands, or slight trembling. The doctor prescribed me Enteric-Coated Fluoxetine...

Dr. Qiu Junda reply Psychiatry
Hello. The side effects of SSRIs are mostly gastrointestinal (such as nausea and vomiting). It is generally advisable to start with a lower dose to see how you respond, as this can help mitigate side effects, which usually become more tolerable within a week. As for Anxiolytics, ...