Duodenal Ulcers: Symptoms, Treatment, and Recovery Time - Gastroenterology and Hepatology

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Duodenal ulcer


Hello Doctor: Recently, I underwent an upper gastrointestinal endoscopy and tested for Helicobacter pylori, which revealed symptoms of duodenal ulcer and gastritis (the Helicobacter pylori test was negative).
However, I have been taking medication for nearly two months without any improvement.
The pain is located in the epigastric area, with a dull ache before and after meals, and I still feel somewhat uncomfortable.
I would like to ask how long I should continue taking the medication before I see improvement, or if there are other treatment options available.
Thank you, Doctor.

Mr. Fang, 10~19 year old female. Ask Date: 2018/01/22

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: If medications are taken on time, it is important to pay attention to diet and lifestyle habits.
Changhua Hospital cares about your health.
Dr.
Tsai An-shun.

Reply Date: 2018/01/22

More Info


Duodenal ulcers, also known as peptic ulcers, are sores that develop on the lining of the duodenum, which is the first part of the small intestine. They can cause a variety of symptoms and may require specific treatment approaches. Understanding the symptoms, treatment options, and recovery time is crucial for managing this condition effectively.


Symptoms of Duodenal Ulcers
The most common symptoms of duodenal ulcers include:
1. Abdominal Pain: This is often described as a burning or gnawing sensation in the upper abdomen, particularly in the epigastric region (the area just below the ribcage). The pain may occur when the stomach is empty, such as between meals or during the night, and may be temporarily relieved by eating or taking antacids.

2. Nausea and Vomiting: Some patients may experience nausea, and in more severe cases, vomiting may occur.

3. Bloating and Indigestion: Patients often report a feeling of fullness, bloating, or discomfort after meals.

4. Loss of Appetite: Due to the pain and discomfort associated with eating, individuals may experience a reduced appetite.

5. Weight Loss: Unintentional weight loss can occur due to decreased food intake.

6. Complications: In severe cases, ulcers can lead to complications such as bleeding, perforation, or obstruction, which may present with symptoms like dark or bloody stools, severe abdominal pain, or signs of shock.


Treatment Options
The treatment for duodenal ulcers typically involves a combination of medications and lifestyle changes:
1. Proton Pump Inhibitors (PPIs): These medications, such as omeprazole or lansoprazole, reduce stomach acid production, promoting healing of the ulcer.

2. H2-Receptor Antagonists: Drugs like ranitidine or famotidine can also decrease acid production and help alleviate symptoms.

3. Antacids: Over-the-counter antacids can provide quick relief from ulcer pain by neutralizing stomach acid.

4. Antibiotics: If an infection with Helicobacter pylori (H. pylori) is present, antibiotics may be prescribed to eradicate the bacteria.

5. Bismuth Compounds: Medications like Pepto-Bismol can help protect the stomach lining and may assist in healing.

6. Lifestyle Modifications: Avoiding irritants such as NSAIDs (non-steroidal anti-inflammatory drugs), alcohol, and smoking can help reduce symptoms and promote healing. Additionally, eating smaller, more frequent meals may alleviate discomfort.


Recovery Time
The recovery time for duodenal ulcers can vary based on several factors, including the severity of the ulcer, adherence to treatment, and individual health conditions. Generally, with appropriate treatment, many patients begin to feel relief within a few weeks. However, complete healing of the ulcer may take several weeks to months. It is essential to follow up with your healthcare provider to monitor progress and make any necessary adjustments to your treatment plan.


When to Seek Further Medical Attention
If you have been on medication for nearly two months without improvement, it is crucial to consult your healthcare provider. They may consider additional diagnostic tests, such as repeat endoscopy, to assess the healing of the ulcer or to rule out other potential issues. Persistent symptoms, especially severe pain, vomiting, or signs of bleeding, warrant immediate medical attention.

In conclusion, managing duodenal ulcers involves a comprehensive approach that includes medication, lifestyle changes, and regular follow-up with your healthcare provider. If you have concerns about your treatment or symptoms, do not hesitate to reach out for further evaluation and support.

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Dr. Cai Anshun reply Gastroenterology and Hepatology
Hello: The health insurance coverage is for 4 months; however, the duration of treatment depends on the severity of the ulcer and your symptoms, which should be discussed with your clinical physician. Changhua Hospital cares about your health. Dr. Tsai An-Shun.

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Dr. Chen Qifeng reply Gastroenterology and Hepatology
Hello: Generally, a treatment course for duodenal ulcers lasts about 6 to 8 weeks, during which the ulcer will heal completely, thereby reducing the chances of recurrence. Best regards, Dr. Chi-Feng Chen, Taoyuan General Hospital, Department of Health.

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