Blood test
Hello Doctor: Recently, I went to the hospital due to blood in my stool.
The doctor performed a physical examination and arranged for blood and stool tests.
The results of the stool occult blood immunoassay showed a value of <7 with a reference value of <30 ng/mL.
The blood test results were as follows: WBC count was 10.5 with a reference range of 3.2-9.2 x 10^3/uL.
NRBC count was 0.1 with a reference range of <0 per 100 WBC.
RBC count was 4.56 with a reference range of 3.72-4.93 x 10^6/uL.
Hemoglobin (Hb) was 13.6 with a reference range of 11.6-14.8 g/dL.
Hematocrit (Hct) was 41.6 with a reference range of 34-44%.
Mean Corpuscular Volume (MCV) was 91.2 with a reference range of 80-100 fL.
Mean Corpuscular Hemoglobin (MCH) was 29.8 with a reference range of 26-34 pg.
Mean Corpuscular Hemoglobin Concentration (MCHC) was 32.7 with a reference range of 31-37 g/dL.
Red Cell Distribution Width (RDW) was 12.1 with a reference range of 11.5-14.5%.
Platelet count was 246 with a reference range of 150-400 x 10^3/uL.
During the consultation, the doctor only mentioned that my hemoglobin level was sufficient and did not address any other issues.
I would like to know what could be the reasons for the elevated WBC (white blood cell) and NRBC (nucleated red blood cell) counts.
Is there any concern? Thank you.
Liú, 30~39 year old female. Ask Date: 2018/02/07
Dr. Huang Xunying reply Family Medicine
Sometimes, asymptomatic infections or colds can lead to elevated white blood cell counts.
As for red blood cells, if hemoglobin levels are normal, a higher red blood cell count is generally not concerning.
A follow-up can be done in three months.
Regarding the presence of blood in the stool, it is recommended to increase the intake of vegetables and fluids.
If bleeding persists, it is advisable to consult a colorectal surgeon for further evaluation to check for hemorrhoids or anal fissures.
Thank you.
Reply Date: 2018/02/07
More Info
Understanding blood test results, particularly elevated white blood cell (WBC) and nucleated red blood cell (NRBC) levels, can be crucial for diagnosing underlying health issues. In your case, the WBC count of 10.5 (with a reference range of 3.2-9.2) indicates leukocytosis, which is an elevated white blood cell count. This condition can arise from various factors, including infections, inflammation, stress, or more serious conditions such as leukemia.
The NRBC count of 0.1 (with a reference range of <0) is also noteworthy. NRBCs are immature red blood cells that typically should not be present in the bloodstream of healthy adults. Their presence can indicate a response to severe stress on the bone marrow, which may occur in conditions such as severe anemia, hypoxia, or bone marrow disorders.
In your case, the elevated WBC could suggest that your body is responding to an infection or inflammation, especially since you mentioned having blood in your stool, which could indicate gastrointestinal issues such as hemorrhoids, diverticulitis, or even more serious conditions like inflammatory bowel disease or malignancies. The presence of NRBCs, while not common, could indicate that your bone marrow is under stress, possibly due to the same underlying issue causing the elevated WBC.
It is essential to consider the context of these results. If you are asymptomatic and your doctor has not expressed concern beyond the hemoglobin levels, it may indicate that the elevation is not currently alarming. However, it is crucial to monitor these levels over time and consider further evaluation, especially if you experience symptoms such as persistent abdominal pain, changes in bowel habits, or any signs of infection (fever, chills, etc.).
In terms of next steps, it would be prudent to follow up with your healthcare provider. They may recommend additional tests, such as a complete blood count (CBC) with differential, blood cultures, or imaging studies to investigate the cause of your symptoms and the abnormal lab results further. If gastrointestinal issues are suspected, a referral to a gastroenterologist might be warranted for further evaluation, including endoscopy or colonoscopy, depending on your symptoms and risk factors.
In summary, elevated WBC and NRBC levels can indicate a range of conditions, from benign to serious. It is essential to interpret these results in conjunction with clinical symptoms and further diagnostic testing. Regular follow-up and communication with your healthcare provider will be key in managing your health and addressing any underlying issues.
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