Zinc Carnosine: A Potential Aid for Stomach Ulcers and GERD - Gastroenterology and Hepatology

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Zinc carnosine and gastric ulcers?


Hello Doctor, in July 2017, an endoscopy revealed a gastric ulcer along with gastroesophageal reflux disease (GERD) (no Helicobacter pylori).
I took Naproxen for five months and stopped on December 15, 2017.
On December 22, 2017, another endoscopy showed the same gastric ulcer with bleeding and worsening gastroesophageal reflux (no Helicobacter pylori).
I have been taking an anti-ulcer medication for two months and would like to ask if taking Zinc Carnosine in addition to the anti-ulcer medication would be beneficial for helping to repair the gastric mucosa and potentially for future gastric maintenance.
Additionally, are there any concerns or precautions regarding this combination? Thank you.
I do not smoke, drink alcohol, or take pain medications.

votto, 30~39 year old female. Ask Date: 2018/02/22

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: 1.
It is not always necessary to add other medications or to take long-term maintenance medications.
If symptoms persist despite medication, short-term use may be sufficient.
2.
Additionally, please be mindful of your coffee or tea consumption, excessive stress, and irregular eating patterns.
Changhua Hospital cares about your health.
Dr.
Tsai An-shun.

Reply Date: 2018/02/22

More Info


Zinc carnosine is a compound that combines zinc with carnosine, a dipeptide that has been studied for its potential benefits in gastrointestinal health, particularly in the context of stomach ulcers and gastroesophageal reflux disease (GERD). Given your history of stomach ulcers and GERD, it is understandable that you are considering the addition of zinc carnosine to your current treatment regimen.

Research has shown that zinc carnosine can play a role in the healing of gastric mucosa. Zinc is an essential mineral that is crucial for numerous biological functions, including immune response, cell division, and wound healing. Carnosine, on the other hand, is known for its antioxidant properties and its ability to stabilize cell membranes. Together, they may help to protect and repair the gastric lining, potentially reducing inflammation and promoting healing in cases of ulcers.

In clinical studies, zinc carnosine has been shown to enhance the healing of gastric ulcers and to provide a protective effect against the damaging effects of non-steroidal anti-inflammatory drugs (NSAIDs) and other irritants. It works by stabilizing the gastric mucosal barrier, increasing mucus production, and promoting the proliferation of gastric epithelial cells. This can be particularly beneficial for individuals like yourself who have experienced recurrent ulcers and GERD symptoms.

Regarding your specific situation, combining zinc carnosine with your current anti-ulcer medication may indeed provide additional support for the healing of your gastric mucosa. However, it is essential to consult with your healthcare provider before adding any new supplement to your regimen. They can help assess your overall health status, review potential interactions with your current medications, and determine the appropriate dosage for your needs.

As for safety and potential side effects, zinc carnosine is generally considered safe for most individuals when taken at recommended doses. However, excessive zinc intake can lead to adverse effects, including nausea, vomiting, diarrhea, and interference with the absorption of other essential minerals, such as copper. Therefore, it is crucial to adhere to the recommended dosage and to monitor for any unusual symptoms.

In addition to considering zinc carnosine, it is also important to address lifestyle factors that may contribute to your GERD and ulcer symptoms. Stress management, dietary modifications, and avoiding known triggers (such as caffeine, spicy foods, and large meals) can significantly impact your gastrointestinal health. Maintaining a balanced diet rich in fruits, vegetables, whole grains, and lean proteins can also support healing and overall well-being.

In summary, zinc carnosine may be a beneficial addition to your treatment plan for stomach ulcers and GERD, but it is essential to discuss this with your healthcare provider to ensure it aligns with your overall treatment strategy. By taking a comprehensive approach that includes both medication and lifestyle modifications, you can work towards better management of your gastrointestinal health.

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