Pearly Penile Papules vs. Fordyce Spots: Key Differences and Removal Options - Urology

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There are some white, pimple-like lesions on the skin?


In January of this year, while showering, I noticed some granular, pimple-like bumps on the front of the frenulum of my penis.
They do not merge together but rather grow in a distinct arrangement.
The next day, I visited a doctor who said that this is not genital warts.
I have not engaged in sexual activity, and upon checking again today, the bumps have not increased in size, but there are more of them.
I researched online and found the terms "pearly penile papules" and "fordyce spots." I would like to ask how to differentiate between pearly penile papules and fordyce spots, as the photos online look similar.
If I want to remove them, what would be the best method? Thank you!

U, 20~29 year old female. Ask Date: 2018/03/07

Dr. Du Shixi reply Urology


Hello: Both are rash-like symptoms, and without examination in this facility, a diagnosis cannot be made.
If you wish to remove them, what would be the best method? → There is no need to remove them.
If you want to confirm, it is recommended to consult a urologist at a hospital.
Wishing you good health.

Reply Date: 2018/03/07

More Info


Pearly penile papules (PPP) and Fordyce spots are two common conditions that can appear on the penis, often causing concern for those who notice them. Understanding the differences between these two conditions, as well as the options for removal, is essential for anyone experiencing these symptoms.

Pearly Penile Papules (PPP) are small, dome-shaped, flesh-colored or white bumps that typically appear in a single row around the corona (the ridge) of the glans (the head of the penis). They are a normal anatomical variant and are not associated with any disease or sexually transmitted infections. PPP is most commonly seen in young adult males and is considered a benign condition. They do not cause any pain or discomfort and do not require treatment unless the individual desires removal for cosmetic reasons.

Fordyce Spots, on the other hand, are small, painless, pale bumps that can appear on the shaft of the penis, the scrotum, or the lips. They are sebaceous glands that are not associated with hair follicles and are completely normal. Fordyce spots can be yellowish or white and are often more prominent in some individuals than others. Like PPP, they are harmless and do not require treatment unless the individual wishes to have them removed for aesthetic reasons.

Key Differences:
1. Location: PPP typically appears around the corona of the glans, while Fordyce spots can be found on the shaft and scrotum.

2. Appearance: PPP are dome-shaped and arranged in a single row, whereas Fordyce spots are flat, slightly raised, and can appear in clusters.

3. Nature: PPP are a normal variant and not a sign of any underlying condition, while Fordyce spots are simply enlarged sebaceous glands.

Removal Options:
If an individual decides to remove either PPP or Fordyce spots, there are several methods available, although it is crucial to consult a healthcare professional before proceeding. Common removal options include:
1. Laser Therapy: This is a popular method for removing PPP. Laser treatment can effectively reduce or eliminate the appearance of these papules with minimal discomfort and downtime.


2. Cryotherapy: This involves freezing the papules with liquid nitrogen, which can cause them to fall off over time. This method is also effective but may require multiple sessions.

3. Electrosurgery: This technique uses electrical currents to remove the papules. It is effective but may leave some scarring.

4. Topical Treatments: While there are no specific topical treatments for PPP, some individuals may consider using topical retinoids for Fordyce spots, although results can vary.

It is important to note that both conditions are benign and do not pose any health risks. If you are unsure whether what you are experiencing is PPP or Fordyce spots, or if you have any concerns about changes in the appearance of your genital area, it is advisable to consult a healthcare provider. They can provide a proper diagnosis and discuss the best options for removal if desired.

In conclusion, while both pearly penile papules and Fordyce spots are common and harmless, understanding their differences can help alleviate concerns. If removal is desired, various options are available, but it is essential to seek professional advice to ensure safe and effective treatment.

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