Pain-Free Gastroscopy and Carbon-13 Testing - Gastroenterology and Hepatology

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Painless gastroscopy and carbon-13?


Dr.
Tsai, Jun-An underwent a "painless gastroscopy" examination this morning.
After waking up, he was informed that "there are no gastric ulcers," and the report indicated "gastroesophageal reflux and esophagitis." He was also told to pay 200 NTD because there were no gastric ulcers.
A carbon-13 urea breath test for Helicobacter pylori was performed and completed, with the results to be reviewed next week.
My question is: how was the carbon-13 urea breath test conducted during the painless gastroscopy? Shouldn't the results for Helicobacter pylori be available immediately? Why do we have to wait until next week's outpatient visit to find out? The doctor has been busy attending to other patients, making it difficult to consult him directly...
Could you please provide some guidance? Thank you.

Chen Yue, 50~59 year old female. Ask Date: 2018/03/13

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: What you underwent was likely not the C13 test (which costs about 1100 NT), but rather the Urease Test (CLO test).
During the endoscopy, gastric mucosal biopsies are taken and placed in a test plate to observe color changes, transitioning from yellow to Congo red.
The reaction time depends on the quantity of bacteria present; typically, reports are not issued on the same day, and some bacteria may take longer to react.
Changhua Hospital cares about your health.
Dr.
Tsai An-Shun.

Reply Date: 2018/03/13

More Info


Understanding the process of a pain-free gastroscopy and the Carbon-13 (C13) Helicobacter pylori test can be quite important for patients undergoing these procedures. Let's break down your questions and concerns regarding these tests.

Firstly, a pain-free gastroscopy, also known as an upper gastrointestinal endoscopy, is a procedure where a flexible tube with a camera (endoscope) is inserted through the mouth to examine the esophagus, stomach, and the beginning of the small intestine (duodenum). This procedure is often performed under sedation to minimize discomfort, hence the term "pain-free." During the gastroscopy, the doctor can visually inspect for abnormalities, take biopsies, and perform other interventions if necessary.

Regarding the Carbon-13 (C13) test for Helicobacter pylori, this is a non-invasive breath test used to detect the presence of H. pylori, a bacterium that can cause stomach ulcers and is associated with gastric cancer. The C13 test involves the patient ingesting a urea solution that contains a carbon isotope (C13). If H. pylori is present in the stomach, it will metabolize the urea, producing carbon dioxide that is then absorbed into the bloodstream and exhaled. The breath sample is collected and analyzed to determine if the C13 isotope is present, indicating an H. pylori infection.

Now, to address your specific questions:
1. How is the C13 test performed during a pain-free gastroscopy?
The C13 test is typically performed after the gastroscopy. During the endoscopy, if the doctor suspects H. pylori infection, they may take a biopsy of the stomach lining. However, the C13 breath test is a separate procedure that can be done on the same day or shortly after the gastroscopy. The results of the C13 test are not immediate because they require laboratory analysis. The breath sample must be processed, which can take time, hence the need for a follow-up appointment to discuss the results.

2. Why can’t you know the results of the C13 test immediately?
The analysis of the breath sample involves specific chemical reactions and measurements that cannot be done instantly. The laboratory needs time to process the sample and determine whether H. pylori is present. This is standard practice for many diagnostic tests, and it ensures accuracy in the results.

3. Concerns about not having ulcers but still having symptoms:
It's important to understand that the absence of ulcers does not mean that there are no underlying issues. Conditions like gastroesophageal reflux disease (GERD) and esophagitis, which were noted in your report, can cause significant discomfort and require management. The presence of H. pylori is a separate concern, as it can lead to ulcers if left untreated.

4. Follow-up and communication with your doctor:
If you have further questions or concerns, it’s crucial to communicate with your healthcare provider. If the doctor is busy, consider reaching out through a patient portal or scheduling a follow-up appointment specifically to discuss your results and any ongoing symptoms.

In summary, the pain-free gastroscopy and C13 test are essential tools in diagnosing gastrointestinal issues. While the wait for results can be frustrating, it is a necessary part of ensuring accurate diagnosis and treatment. If you have ongoing symptoms, it is important to continue discussing them with your healthcare provider to find the best management plan for your situation.

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