Gastrointestinal Issues: Concerns About Medication and Cancer Risks - Gastroenterology and Hepatology

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Continuing from consultation 134027, I apologize for bothering you again regarding my gastrointestinal issues?


Hello, doctor.
I apologize for bothering you again.
In my previous consultation with Dr.
134027, you mentioned that the dysfunction syndrome refers to the gastrointestinal tract, correct? I am really uncomfortable, and later I consulted another doctor who did not perform an endoscopy.
I have had several endoscopies in the past, and the doctors always said that my throat is tighter and more sensitive.
(The last endoscopy was about 1-2 years ago.) The doctor mentioned indigestion and gastroesophageal reflux.
However, I felt that the consultation was very brief, and I didn’t have the chance to ask detailed questions.
Therefore, I would like to ask for your recommendation for a doctor.

I have one last question based on your clinical experience.
Besides what is already happening, could taking anti-inflammatory medication for 5-6 months without accompanying gastric medication, as well as taking sleeping pills for insomnia, lead to stomach cancer? How long after the onset of the disease does stomach cancer typically become treatable? As a single parent, I am considering the costs and did not opt for a painless procedure; the traditional method without anesthesia is very uncomfortable, and the doctor cannot conduct a thorough examination...
I really don’t know what to do.
Thank you very much, doctor.
I appreciate it.

Awei, 30~39 year old female. Ask Date: 2018/03/19

Dr. Chen Qifeng reply Gastroenterology and Hepatology


Taking anti-inflammatory medication for 5-6 months without accompanying gastric protection will not cause stomach cancer, nor will taking sleeping pills for insomnia lead to stomach cancer.
Based on the symptoms, this is classified as gastrointestinal dysfunction.
If you need to examine the esophagus, stomach, and duodenum, a barium swallow study can be used as an alternative.

Reply Date: 2018/03/19

More Info


When it comes to gastrointestinal health and the potential risks associated with certain medications and conditions, it's essential to understand the nuances involved. Your concerns about the relationship between medications, such as anti-inflammatory drugs and sleep aids, and the risk of developing gastric cancer are valid and warrant a thorough discussion.

Firstly, the use of non-steroidal anti-inflammatory drugs (NSAIDs) over an extended period can indeed lead to gastrointestinal issues, including gastritis and peptic ulcers. These conditions can cause discomfort and may increase the risk of complications, such as bleeding or perforation. However, the direct link between long-term NSAID use and gastric cancer is not as straightforward. While chronic inflammation and ulceration of the gastric mucosa can contribute to an increased risk of malignancy, it is not a guaranteed outcome. The development of gastric cancer is multifactorial, involving genetic predispositions, environmental factors, and the presence of certain infections, notably Helicobacter pylori.

Regarding your use of sleep aids, while they can help manage insomnia, they are not typically associated with an increased risk of gastric cancer. However, if they lead to gastrointestinal side effects, such as nausea or changes in appetite, it might be worth discussing with your healthcare provider.

As for the timeline of gastric cancer development, it is important to note that gastric cancer often develops over many years, typically arising from precancerous conditions such as chronic gastritis or intestinal metaplasia. Regular monitoring and early detection are crucial. If you have risk factors, such as a family history of gastric cancer or chronic H. pylori infection, it is advisable to have regular check-ups and screenings.

In terms of your gastrointestinal symptoms, including discomfort and the sensation of tightness in your throat, these could be related to gastroesophageal reflux disease (GERD) or functional dyspepsia. It is not uncommon for patients to experience these symptoms without significant findings on endoscopy, especially if the examination is not thorough. If you feel that your concerns are not being adequately addressed, seeking a second opinion or consulting a gastroenterologist who specializes in functional gastrointestinal disorders may provide you with more comprehensive care.

In conclusion, while there are risks associated with long-term medication use, the development of gastric cancer is influenced by a variety of factors. It is crucial to maintain open communication with your healthcare provider, discuss your symptoms in detail, and consider regular screenings, especially if you have risk factors for gastric cancer. If financial constraints are a concern, inquire about options for subsidized care or community health services that may offer more affordable diagnostic procedures. Your health is paramount, and addressing these issues proactively can lead to better outcomes.

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