Moles: When to Worry About Skin Cancer Risks - Dermatology

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Concerns about Moles


The mole on the bottom of my toe has been there for one to two years.
I haven't paid much attention to its shape, but it is irregular and should be less than 5 cm.
Recently, I've experienced very brief pain, which feels strange, especially since it’s near the mole.
I'm wondering if this could be skin cancer or if it’s related to puberty.

Tommy, 10~19 year old female. Ask Date: 2018/03/25

Dr. Wu Yuxin reply Dermatology


5 centimeters? That's quite large.
It's best to seek medical attention for confirmation.

Reply Date: 2018/03/25

More Info


When it comes to moles and their potential association with skin cancer, it's important to understand the characteristics that can indicate a higher risk. The presence of an irregularly shaped mole, especially one that has changed in size, shape, or color, can be a cause for concern. The fact that you mentioned the mole on your toe has been present for one to two years and is irregular in shape is noteworthy. Additionally, the recent onset of pain in or around the mole is another factor that warrants attention.

Moles, or nevi, are common skin growths that can be benign (non-cancerous) or malignant (cancerous). The most common type of skin cancer associated with moles is melanoma, which can develop from existing moles or appear as new growths on the skin. The ABCDE rule is a helpful guideline for assessing moles:
- Asymmetry: One half of the mole does not match the other half.

- Border: The edges are irregular, ragged, or blurred.

- Color: The color is not uniform and may include shades of brown, black, or even red, white, or blue.

- Diameter: The mole is larger than 6mm (about the size of a pencil eraser), although melanomas can be smaller.

- Evolving: The mole is changing in size, shape, or color.

Given that your mole is irregular and has recently started to cause pain, it is advisable to consult a dermatologist as soon as possible. Pain in a mole can sometimes indicate irritation or changes that may be associated with malignancy. While pain alone does not confirm skin cancer, it is a symptom that should not be ignored, especially in conjunction with other concerning features.

In terms of the relationship between moles and skin cancer, it is essential to note that while most moles are harmless, certain types, particularly atypical moles (dysplastic nevi), can increase the risk of developing melanoma. Factors such as family history of skin cancer, excessive sun exposure, and having many moles can also elevate this risk.

If you are concerned about the mole, a dermatologist will likely perform a thorough examination and may recommend a biopsy, where a small sample of the mole is removed and examined under a microscope. This is the most definitive way to determine whether a mole is benign or malignant.

In summary, while not all irregular moles are cancerous, the combination of irregular shape, recent changes, and pain should prompt a visit to a healthcare professional. Early detection is key in the successful treatment of skin cancer, and addressing any concerns promptly can lead to better outcomes. Remember to protect your skin from excessive sun exposure by using sunscreen and wearing protective clothing, as these are important preventive measures against skin cancer.

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