Do I Need Further Testing for Positive Hepatitis B Surface Antigen? - Gastroenterology and Hepatology

More Info

---

Based on your inquiry regarding the positive Hepatitis B surface antigen (HBsAg) result from your blood donation screening, it is crucial to understand the implications of this finding and the necessary steps you should take moving forward.

Firstly, a positive HBsAg indicates that you are currently infected with the Hepatitis B virus (HBV). This does not necessarily mean that you have active disease or that you will experience severe health issues, but it does require further evaluation. The presence of HBsAg suggests that the virus is replicating in your body, and you may be contagious to others. Therefore, it is essential to follow up with a healthcare provider, preferably a gastroenterologist or a hepatologist, for a comprehensive assessment.

In your case, since your liver function tests (LFTs) were normal during your health check, this is a positive sign. Normal liver function tests suggest that there is no immediate liver damage or inflammation. However, it is important to note that liver function can remain normal even in the presence of chronic Hepatitis B infection, especially in the early stages or in cases where the infection is inactive.

Further testing is warranted to determine the extent of your infection and to assess your liver health. The following tests are typically recommended:
1. HBeAg and Anti-HBe Testing: These tests help determine the level of viral replication and the stage of the infection. A positive HBeAg indicates active viral replication, while the presence of Anti-HBe suggests that the virus is less active.

2. HBV DNA Quantification: This test measures the amount of virus in your blood. It is crucial for assessing the level of viral replication and determining the need for antiviral treatment.

3. Liver Ultrasound: An ultrasound can help evaluate the liver's structure and check for any signs of liver damage, cirrhosis, or liver cancer.

4. Liver Biopsy or FibroScan: If there is concern about liver damage, a biopsy or a non-invasive test like FibroScan may be performed to assess the degree of fibrosis or cirrhosis.

5. Serological Tests for Other Hepatitis Viruses: It is also prudent to test for other hepatitis viruses (such as Hepatitis C) to rule out co-infections.

In summary, while your normal liver function tests are reassuring, the positive HBsAg result necessitates further evaluation to understand the nature of your Hepatitis B infection. It is essential to consult with a healthcare provider who can guide you through the necessary tests and help you understand your condition better. Early detection and monitoring are key to managing Hepatitis B effectively and preventing potential complications in the future.