Thyroid Fluctuations: When to Seek Further Evaluation - Breast and Thyroid

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Thyroid abnormalities?


Hello doctor, I often feel unwell, experiencing palpitations, chest tightness, slight tremors, low mood, and poor physical strength.
I have been diagnosed with anxiety disorder and panic disorder...
I have been under continuous monitoring for a year, and my test results are actually within the normal range with no abnormal values.
However, the only thing that confuses the doctor is why my endocrine thyroid indices (I can't remember the specific names) fluctuate so much.
Although they are all within the normal range, they are either too high or too low.
For example, if the normal range is 1-10, I might be at 2 this time and 8 or 9 last time (just as an analogy).
All of this has been checked in family medicine, and the doctor has not considered referring me...
Today, the doctor told me that normal individuals do not experience such significant fluctuations, and if my blood test results continue to vary wildly next time, they will arrange for a CT scan or MRI of the brain to check for a possible pituitary tumor.
P.S.
My menstrual cycle is normal, and I do not have sparse body hair, but I have gained 16 kilograms over the past two years (I have a big appetite and do not exercise).
May I ask the specialist if you would also recommend further examinations?

Miss Zheng, 20~29 year old female. Ask Date: 2018/04/19

Dr. Yuan Tianmin reply Breast and Thyroid


You are already in consultation; if necessary, your physician will refer you.

Reply Date: 2018/04/19

More Info


It sounds like you are experiencing a range of symptoms that are causing you concern, and it's understandable to seek clarity on your thyroid function and overall health. Based on your description, you have been experiencing symptoms such as palpitations, chest tightness, tremors, low mood, and fatigue, which can indeed overlap with anxiety disorders. However, the fluctuations in your thyroid hormone levels, despite remaining within the normal range, warrant further investigation.

Thyroid hormones, primarily T3 (triiodothyronine) and T4 (thyroxine), play a crucial role in regulating metabolism, energy levels, and overall bodily functions. The pituitary gland, located at the base of the brain, produces TSH (thyroid-stimulating hormone), which regulates the production of T3 and T4. If your thyroid hormone levels are fluctuating significantly, even within the normal range, it could indicate an underlying issue with how your body is regulating these hormones.

The symptoms you describe—heart palpitations, anxiety, and fatigue—can be associated with both hyperthyroidism (overactive thyroid) and hypothyroidism (underactive thyroid). In your case, the variability in your thyroid hormone levels could suggest that your body is struggling to maintain a stable hormonal balance, which might be due to several factors, including stress, diet, lifestyle, or even a potential thyroid disorder.

Given that your primary care physician has suggested the possibility of a pituitary tumor if these fluctuations continue, it is prudent to consider further evaluation. A pituitary tumor can affect hormone production and regulation, leading to symptoms similar to what you are experiencing. An MRI of the brain can help visualize the pituitary gland and rule out any abnormalities.

Additionally, it may be beneficial to consult with an endocrinologist, a specialist in hormone-related disorders. They can provide a more comprehensive evaluation of your thyroid function and other endocrine systems. They may recommend additional tests, such as measuring thyroid antibodies to check for autoimmune thyroid disease (like Hashimoto's thyroiditis or Graves' disease), or conducting a more detailed assessment of your pituitary function.

In the meantime, consider lifestyle modifications that can help manage your symptoms. Regular exercise, a balanced diet, stress management techniques (such as mindfulness or yoga), and adequate sleep can all contribute to improved overall well-being and may help stabilize your hormone levels.

In summary, while your thyroid hormone levels are currently within the normal range, the significant fluctuations and your ongoing symptoms suggest that further evaluation is warranted. Consulting with an endocrinologist and possibly undergoing imaging studies can provide clarity and help guide appropriate treatment. Your health is important, and seeking the right care is a proactive step towards feeling better.

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