Is It Necessary to Use Bone Growth Injection for Clavicle Fracture Recovery? - Orthopedics

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Clavicle fracture


I would like to ask about a 65-year-old elderly person who suffered a clavicle fracture in a car accident in mid-March.
After seeking medical attention, the doctor stated that surgery is not currently necessary and that a brace should be worn.
The frequency of follow-up visits has changed from once a week to once every three weeks.
The doctor mentioned a certain beneficial self-funded injection, which research has shown can promote bone growth, but it costs between $15,000 and $18,000 for a one-month treatment (I apologize for forgetting the name).
I would like to know if this injection is necessary.

Z, 20~29 year old female. Ask Date: 2018/04/26

Dr. Wang Shouji reply Orthopedics


Hello: If a clavicle fracture does not require surgery, it can be protected with a triangular sling and figure-eight bandage for monitoring.
Forteo (teriparatide) is originally used to stimulate bone growth in osteoporosis, but there is no evidence to support that it accelerates fracture healing, and its routine use is not recommended.

Reply Date: 2018/04/26

More Info


When it comes to the recovery from a clavicle fracture, especially in an elderly patient, the decision to use a bone growth injection should be carefully considered. In your case, the patient is a 65-year-old individual who suffered a clavicle fracture from a car accident. The initial treatment involved a non-surgical approach with a brace, which is common for many clavicle fractures, particularly when they are not displaced or severely complicated.

The use of bone growth injections, such as platelet-rich plasma (PRP) or other bone-stimulating agents, has gained popularity in recent years. These injections are thought to enhance the healing process by providing growth factors that promote bone regeneration. Research indicates that these treatments can be beneficial in certain cases, particularly for patients with delayed healing or non-union fractures. However, the effectiveness can vary widely among individuals.

In your situation, the doctor has mentioned that the injection has been shown to help with bone growth, but it comes at a significant cost (around $15,000 to $18,000). Here are several factors to consider when deciding whether to proceed with this treatment:
1. Current Healing Progress: Since the patient has been monitored with follow-up appointments every three weeks, it is essential to assess how well the fracture is healing. If the X-rays show signs of healing and the patient is experiencing minimal pain, it may indicate that the body is healing adequately without additional interventions.

2. Age and Overall Health: The age of the patient can influence healing capacity. Older adults often have slower healing processes due to factors such as decreased bone density and slower cellular regeneration. However, if the patient is otherwise healthy and has no significant comorbidities, they may still heal well with conservative management.

3. Potential Risks and Benefits: While bone growth injections can potentially enhance healing, they are not without risks. Side effects can include pain at the injection site, infection, or allergic reactions. It is crucial to weigh these risks against the potential benefits of accelerated healing.

4. Cost vs. Necessity: The financial aspect is also significant. If the injection is not deemed medically necessary and the fracture is healing well, it may be more prudent to avoid the expense. Discussing with the healthcare provider about the necessity of the injection based on the current healing status is essential.

5. Alternative Treatments: If there are concerns about the healing process, other options such as physical therapy, nutritional support (ensuring adequate calcium and vitamin D intake), and possibly revisiting the decision for surgical intervention if healing does not progress could be considered.

In conclusion, while bone growth injections can be beneficial in specific cases, they are not universally necessary for all fractures. It is essential to have a thorough discussion with the treating physician about the current status of the fracture, the expected healing timeline, and whether the potential benefits of the injection justify the cost and risks involved. Regular follow-ups and monitoring will provide the best insight into whether additional interventions are needed.

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