Non-Reactive Hepatitis B Surface Antigen Test Results - Gastroenterology and Hepatology

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Hepatitis B testing


Hello Dr.
Tsai: May I ask if a Hepatitis B surface antigen test result of Non-reactive 0.44, which is less than the reference value of Non-reactive (<0.9), indicates a negative result (meaning no Hepatitis B)? Thank you!

YOYO, 40~49 year old female. Ask Date: 2018/04/30

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: Yes! A negative surface antigen means there is no hepatitis B.
Changhua Hospital cares about your health.
Dr.
Tsai An-Shun.

Reply Date: 2018/04/30

More Info


When you receive a Non-Reactive result for the Hepatitis B Surface Antigen (HBsAg) test, it generally indicates that you are not currently infected with the Hepatitis B virus (HBV). In your case, with a result of 0.44, which is below the reference value of <0.9, it confirms that you do not have an active Hepatitis B infection. This is a positive outcome, as it suggests that your liver is not currently being affected by the virus.

The HBsAg test is crucial in diagnosing Hepatitis B. A Non-Reactive result means that the virus is not present in your bloodstream at detectable levels. This is an important distinction because Hepatitis B can lead to chronic liver disease, cirrhosis, and even liver cancer if left untreated. Therefore, a negative result is reassuring.

However, it is also important to consider the Hepatitis B Surface Antibody (anti-HBs) test. If this test is Reactive, it indicates that you have developed immunity to the virus, either through vaccination or past infection. If your anti-HBs result is Non-Reactive, it means you do not have immunity against Hepatitis B. In such cases, if you are at risk of exposure to the virus—such as through healthcare work or other high-risk activities—considering vaccination against Hepatitis B would be advisable.

In summary, your Non-Reactive HBsAg result suggests that you are not currently infected with Hepatitis B. If you have not been vaccinated and your anti-HBs is Non-Reactive, you may want to discuss vaccination options with your healthcare provider to protect yourself against potential future infections.

It is also worth noting that Hepatitis B can have a window period where the virus is present but not detectable by the HBsAg test. This is typically rare, but if you have had recent exposure or are experiencing symptoms, your doctor may recommend additional testing, such as the Hepatitis B core antibody (anti-HBc) test, to provide a more comprehensive understanding of your Hepatitis B status.

In conclusion, your test results indicate that you are not currently infected with Hepatitis B, and if you have concerns about your immunity status, further discussions with your healthcare provider about vaccination and additional testing can help ensure your long-term health and safety.

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