Pregnancy Medication Concerns: Impact of Dermatological Treatments on Fetal Health - Obstetrics and Gynecology

Share to:

Questions about medication during pregnancy?


Hello, my last menstrual period started on April 5th, and I haven't gotten my period this month.
On May 5th, a pregnancy test showed a faint second line, and on May 8th, the second line was clearly visible.
I have been dealing with acne issues and have been seeing a dermatologist since February, using the following medications (I stopped using them on May 5th after the pregnancy test).
I would like to know if these medications could affect the fetus.
My scheduled obstetrician appointment is not until mid-June; should I seek earlier evaluations? The dermatological medications I used are: (Oral - taken twice daily) DOXYCYCLINE and DOXMEQUITAZINE MEQICOMEINTONSTAN (Topical - applied to the entire face) DERMALEAN GE DER----> applied to the entire face and chest/back (daily) ADARIN GEL 0 ADA1---> the pharmacist mentioned this is a retinoid (used almost daily in March) AI CREAM AI-----> used only when my face is dry.
I am particularly concerned because I have been on these medications for a while and have been using a retinoid topically, so I wonder if I need to undergo any special tests.

MIA, 30~39 year old female. Ask Date: 2018/05/12

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, based on your description of the pregnancy safety classifications of medications, most fall under category B or C, which can be used if necessary.
Doxycycline is classified as category D, and the classification of retinoic acid varies depending on its formulation and dosage.
It is recommended to consult with the prescribing physician regarding the timing and dosage of the medication, and then discuss it with your obstetrician.
Thank you! Wishing you safety and health.
Dr.
Chang.

Reply Date: 2018/05/12

More Info


When it comes to the use of dermatological medications during pregnancy, it is crucial to consider both the safety of the medications and their potential effects on fetal health. Your concerns regarding the medications you have been using, particularly Doxycycline, Doxmequitazine, and topical retinoids (like Adarin Gel, which contains tretinoin), are valid, especially since you have recently confirmed your pregnancy.

Doxycycline is a tetracycline antibiotic that is generally classified as a Category D medication during pregnancy. This means that there is evidence of risk to the fetus, particularly regarding potential effects on bone growth and tooth discoloration if taken during the second and third trimesters. Given that you stopped taking Doxycycline upon confirming your pregnancy, this is a prudent decision. However, it is essential to discuss any lingering effects with your healthcare provider.

Doxmequitazine, an antihistamine, is less commonly discussed in pregnancy contexts. While it is classified as Category C, meaning that risk cannot be ruled out, there is limited data on its effects during pregnancy. It is advisable to consult your healthcare provider regarding this medication, especially since you have already stopped its use.

Topical retinoids, such as tretinoin (found in Adarin Gel), are also classified as Category C. While there is no definitive evidence that topical retinoids cause harm when used during pregnancy, they are generally advised against due to the potential for systemic absorption, especially with prolonged use. Since you mentioned using it almost daily, it would be wise to discontinue its use and consult with your healthcare provider about alternative treatments for acne that are safer during pregnancy.

Given your history of using these medications, it is essential to have a thorough discussion with your obstetrician as soon as possible. While your appointment is not until mid-June, you may want to consider reaching out to your healthcare provider for an earlier consultation. They may recommend specific prenatal screenings or ultrasounds to monitor fetal development, especially considering the medications you have used.

In addition to discussing your medication history, it is also important to address any ongoing skin concerns with your dermatologist. They can provide guidance on safe alternatives for managing acne during pregnancy, such as certain topical treatments that do not contain retinoids or antibiotics.

In summary, while you have taken the right steps by discontinuing the medications upon confirming your pregnancy, it is crucial to have open communication with both your obstetrician and dermatologist. They can help you navigate your skin care needs safely while ensuring the health of your developing fetus. Regular prenatal check-ups and monitoring will be vital in addressing any potential concerns that may arise from your previous medication use.

Similar Q&A

Impact of Medications on Fetal Development: Concerns and Considerations

Hello, pharmacist. I started taking Vibramycin (an antibiotic) and Prednisolone (an immunosuppressant for allergy treatment) at the end of June due to acne. Later, I took Erispan, Deanxit, and Secorin Doxylamine succinate 25 mg for about three weeks because I was feeling down. Th...


Dr. Zhang Jinteng reply Pharmacology
Hello, in response to your question: Based on your description and the medications you are using, the most significant drugs that may have an impact are dermatological medications and antifungal agents. Here is the information regarding the pregnancy medication categories for you...

[Read More] Impact of Medications on Fetal Development: Concerns and Considerations


Pregnancy and Medication: Safety Concerns for Skin Treatments

I am currently three months pregnant. Recently, I developed dyshidrotic eczema on the soles of my feet. A dermatologist prescribed me a topical medication and mentioned that it is safe to use during pregnancy as long as I avoid taking oral medications. However, I have heard that ...


Dr. Hou Fangmin reply Pharmacology
Hello; Bestasol cream is a topical ointment classified as pregnancy category C, with categories ranging from A to X, where the latter indicates increasing severity. Therefore, caution is still advised. Ureson cream is also classified as pregnancy category C, and extra care should...

[Read More] Pregnancy and Medication: Safety Concerns for Skin Treatments


Impact of Topical Retinoids During Pregnancy: Risks and Concerns

I am 16 weeks pregnant now, but during the early stages, I had acne and used a third-generation moisturizer that contains retinoids on my face for about two months. Later, I heard that it could affect the baby and cause birth defects, so I stopped using it at 13 weeks. Will this ...


Dr. Chen Changfu reply Obstetrics and Gynecology
Dear netizens: Hello! Most topical medications for skin treatment are absorbed into the body in very small amounts. Currently, there are no reports or warnings in obstetric clinical practice indicating that moisturizing creams cause fetal malformations, so the likelihood of affec...

[Read More] Impact of Topical Retinoids During Pregnancy: Risks and Concerns


Impact of Medications on Fetal Development: A Concern for Expecting Mothers

In this case, the girlfriend was unaware of her pregnancy and was treated for urethritis. The doctor prescribed the following medications for three days: 1. 500mg Refexin, four tablets daily; 2. 100mg Tonec, two tablets daily. After a brief improvement, the symptoms recurred, and...


Dr. Yang Wangjun reply Obstetrics and Gynecology
Hello: Refexin (cephalexin) is a first-generation cephalosporin. It is classified as a Category B medication during pregnancy, which means it can be used while pregnant. Tonec is a non-steroidal anti-inflammatory drug (NSAID), and this medication is not included in the pregnancy ...

[Read More] Impact of Medications on Fetal Development: A Concern for Expecting Mothers


Related FAQ

Pregnancy Medication

(Obstetrics and Gynecology)

Skin

(Obstetrics and Gynecology)

Drug Side Effects

(Obstetrics and Gynecology)

Folliculitis

(Obstetrics and Gynecology)

Menstrual Regulation Medication

(Obstetrics and Gynecology)

Abortion Pill

(Obstetrics and Gynecology)

Fetus

(Obstetrics and Gynecology)

Genital Itching

(Obstetrics and Gynecology)

Pregnancy Bleeding

(Obstetrics and Gynecology)

Medication To Delay Menstruation

(Obstetrics and Gynecology)