Post-Hepatitis B Test Results: What You Need to Know - Gastroenterology and Hepatology

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Questions After Hepatitis B Testing


Hello Dr.
Tsai: I underwent a hepatitis B test, and the results are as follows: (1) Test item: Anti HCV, Result: Negative (0.06) S/CO (2) Test item: HBc IgG (Hepatitis B core antibody), Result: Positive (3) Test item: HBs Ag (Hepatitis B surface antigen), Result: Negative (0.19) S/CO.
I consulted with the doctor, who said, "You have had hepatitis B in the past, but you are no longer a carrier.
However, you still need to monitor liver function and undergo ultrasound every six months." I would like to ask, does being no longer a carrier mean that there is no hepatitis B virus in the liver? If so, why is it necessary to continue monitoring every six months? Thank you for clarifying.

YOYO, 60~69 year old female. Ask Date: 2018/06/01

Dr. Cai Jinji reply Gastroenterology and Hepatology


If one is not a carrier, the likelihood of having hepatitis B virus in the liver is relatively low (with very few exceptions).
However, since there was a previous history of being a hepatitis B carrier, it indicates that there has been a liver condition in the past.
Therefore, regular monitoring is still necessary to check for any changes.

Reply Date: 2018/06/01

More Info


Understanding your hepatitis B test results can be quite complex, but it’s crucial for managing your health effectively. Based on the results you've provided, let's break down what each component means and why continued monitoring is necessary.

1. Anti-HCV (Hepatitis C Antibody): Your test result is negative (0.06 S/CO), indicating that you have not been infected with the Hepatitis C virus. This is a good sign, as it means you are not currently dealing with a Hepatitis C infection.

2. HBc IgG (Hepatitis B Core Antibody): Your result is positive. This indicates that you have been exposed to the Hepatitis B virus at some point in your life. The presence of IgG antibodies suggests that your body has mounted an immune response to the virus, which typically occurs after an acute infection or as a result of chronic infection that has resolved.

3. HBsAg (Hepatitis B Surface Antigen): Your result is negative (0.19 S/CO). This is significant because HBsAg is a marker for active Hepatitis B infection. A negative result means that you are not currently a carrier of the virus, which aligns with your doctor's interpretation that you are not a chronic carrier.


Interpretation of Results
From your results, it can be concluded that you have had a past infection with Hepatitis B, but you are not currently infected or a carrier. This is often referred to as having "resolved" Hepatitis B. In many cases, individuals who have cleared the virus will develop antibodies (anti-HBs) that protect them from future infections.


Why Continued Monitoring?
Even though you are not a carrier and do not have an active infection, there are several reasons why your doctor recommends monitoring every six months:
1. Liver Health: Hepatitis B can cause liver damage, and even after the virus is cleared, there may be residual effects on liver function. Regular liver function tests (like ALT and AST) can help monitor for any ongoing liver issues.

2. Risk of Reactivation: In some cases, the virus can reactivate, especially if the immune system is compromised. Regular monitoring helps catch any potential reactivation early.

3. Liver Cancer Screening: Individuals with a history of Hepatitis B, even if resolved, may have an increased risk of developing liver cancer (hepatocellular carcinoma) later in life. Regular ultrasounds can help in early detection.

4. Overall Health Management: Regular check-ups allow for a comprehensive approach to your health, ensuring that any other potential issues are addressed promptly.


Conclusion
In summary, your test results indicate that you have successfully cleared a past Hepatitis B infection and are not currently a carrier. However, the recommendation for biannual monitoring is a precautionary measure to ensure your liver remains healthy and to catch any potential issues early. It’s essential to follow your doctor’s advice and maintain regular check-ups to safeguard your health. If you have any further questions or concerns, don’t hesitate to discuss them with your healthcare provider.

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