Effective Treatments for Psoriasis: Topical Options and Steroid Precautions - Dermatology

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Recommendations for the treatment of psoriasis?


1.
Can psoriasis be treated with over-the-counter topical medications? If so, please recommend the names of the medications along with the duration and frequency of use.

2.
What are the contraindications for general corticosteroids?

Wisley, 40~49 year old female. Ask Date: 2000/11/28

Dr. Zheng Lizhen reply Dermatology


Hello: Regarding the first point, it is best for you to visit a dermatologist in person for a diagnosis by a physician, rather than attempting to manage it on your own.
As for the second point regarding the contraindications of steroids, to put it simply, steroids are contraindicated in infectious diseases.

Reply Date: 2000/11/28

More Info


Psoriasis, commonly known as psoriasis vulgaris, is a chronic autoimmune condition characterized by the rapid proliferation of skin cells, leading to thick, red, scaly patches on the skin. While it can be a challenging condition to manage, there are effective treatments available, particularly topical options.
1. Topical Treatments for Psoriasis:
For mild to moderate psoriasis, topical treatments can be quite effective. These include:
- Corticosteroids: These are anti-inflammatory medications that can help reduce redness and swelling. Commonly used corticosteroids include hydrocortisone, betamethasone, and clobetasol. The strength of the steroid should be chosen based on the severity of the psoriasis and the area being treated. For example, stronger steroids like clobetasol are often used for thicker plaques, while milder ones like hydrocortisone may be used for sensitive areas. Typically, these can be applied once or twice daily for a duration of 2-4 weeks, but long-term use should be monitored by a healthcare provider to avoid side effects such as skin thinning.

- Vitamin D Analogues: Calcipotriene and calcitriol are examples that can help slow skin cell growth. These can be used in conjunction with corticosteroids to enhance efficacy. They are usually applied once or twice daily.

- Retinoids: Topical retinoids like tazarotene can help normalize skin cell growth and reduce inflammation. They are generally applied once daily at night.

- Coal Tar: This is an older treatment that can reduce scaling, itching, and inflammation. It is available in various formulations, including shampoos, ointments, and creams. It can be used daily or several times a week.

- Moisturizers: Regular use of emollients can help manage dryness and scaling associated with psoriasis. They should be applied liberally after bathing and throughout the day.

2. Corticosteroid Precautions:
While corticosteroids can be effective, there are important precautions to consider:
- Tachyphylaxis: This refers to the phenomenon where the effectiveness of a medication diminishes with continuous use. To prevent this, it is often recommended to use corticosteroids intermittently or in rotation with other topical treatments.

- Skin Atrophy: Prolonged use of potent topical steroids can lead to thinning of the skin, especially in sensitive areas like the face and groin. Therefore, it is crucial to follow a healthcare provider's guidance on the duration and strength of steroid use.

- Rebound Effect: Discontinuing corticosteroids abruptly can sometimes lead to a rebound flare of psoriasis. Gradual tapering may be necessary.

- Systemic Absorption: High-potency steroids or occlusive dressings can lead to systemic absorption, which may cause side effects such as adrenal suppression. Monitoring by a healthcare provider is essential, especially in long-term use.

In conclusion, while psoriasis can be effectively managed with topical treatments, it is essential to approach treatment with caution, particularly when using corticosteroids. Regular follow-ups with a dermatologist can help tailor the treatment plan to the individual’s needs and monitor for any potential side effects. If over-the-counter options do not provide relief, or if the condition worsens, seeking professional medical advice is crucial for more advanced therapies, including phototherapy or systemic medications.

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