Chlamydia Treatment: Do I Need a Third Week of Antibiotics? - Urology

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Treatment for Mycoplasma Infection


I was treated for a Mycoplasma infection with 7 days of Minocycline, followed by another 7 days of Doxycycline, totaling 14 days of antibiotic treatment.
Since I took two different antibiotics, I am concerned about the effectiveness of the treatment.
Should I continue with a third week of antibiotics, or is it unnecessary? Thank you.

Maike, 50~59 year old female. Ask Date: 2018/08/02

Dr. Chen Jiansheng reply Urology


Theoretically, treatment has been completed, and a follow-up test can be conducted to determine if any pathogens are still present.

Reply Date: 2018/08/02

More Info


When it comes to treating Chlamydia infections, the standard treatment typically involves a course of antibiotics. In your case, you have already completed a total of 14 days of antibiotic therapy, first with Minocycline for 7 days and then with Doxycycline for another 7 days. This combination is generally considered effective for treating Chlamydia, as both antibiotics are known to target the bacteria responsible for the infection.

The Centers for Disease Control and Prevention (CDC) recommends several treatment options for Chlamydia, including a single dose of Azithromycin or a 7-day course of Doxycycline. The regimen you followed, which included two different antibiotics over a span of 14 days, is more than sufficient for most cases. The concern about needing a third week of antibiotics typically arises when there are complications or if the infection does not respond to initial treatment. However, if you have completed the prescribed course and are not experiencing any persistent symptoms, it is unlikely that you need to continue treatment for a third week.

It is important to monitor for any symptoms that may suggest the infection has not been fully resolved, such as unusual discharge, pelvic pain, or discomfort during urination. If you experience any of these symptoms, it would be prudent to follow up with your healthcare provider for further evaluation. They may recommend a test of cure, which is a follow-up test to ensure that the infection has been completely cleared.

Additionally, it is worth noting that antibiotic resistance is a concern in any bacterial infection. However, the likelihood of developing resistance to Minocycline or Doxycycline after a standard treatment course is low, especially if the medications were taken as prescribed. If you have concerns about the effectiveness of your treatment or potential resistance, discussing these with your healthcare provider can provide clarity and reassurance.

In summary, based on the information provided, it is generally not necessary to extend your antibiotic treatment to a third week after completing 14 days of therapy with Minocycline and Doxycycline for Chlamydia. However, if you have any lingering symptoms or concerns, it is always best to consult with your healthcare provider for personalized medical advice. They can assess your situation and determine if any further treatment or testing is needed.

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