Fresh Blood in Stool Despite Clean Colonoscopy Results - Gastroenterology and Hepatology

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The colon is very clean, yet there is blood in the stool?


Hello Doctor: I had a colonoscopy in May of this year, during which small polyps were removed and my colon was clean with no lesions.
However, recently I have been experiencing fresh blood in my stool.
What could be the possible reasons for this? Besides issues related to the colon, what other bodily problems could be suspected when there is fresh blood in the stool? Thank you, Doctor.

Miss Huang, 40~49 year old female. Ask Date: 2018/08/02

Dr. Chen Qifeng reply Gastroenterology and Hepatology


This condition should consider hemorrhoids or anal fissures; please consult a colorectal surgeon.

Reply Date: 2018/08/02

More Info


Experiencing fresh blood in your stool can be concerning, especially after having undergone a colonoscopy that yielded clean results. It's important to understand that while a colonoscopy is a valuable diagnostic tool, it does not rule out all potential causes of rectal bleeding.
Firstly, the presence of fresh blood in the stool can be attributed to several factors, and not all of them are related to the colon itself. Given that your colonoscopy was clear and showed no signs of polyps or hemorrhoids, we should consider other potential sources of bleeding. Here are a few possibilities:
1. Hemorrhoids: Even if your colonoscopy did not reveal hemorrhoids, they can still develop or become symptomatic after the procedure. Internal or external hemorrhoids can cause bright red blood on the surface of the stool or on toilet paper after wiping.

2. Anal Fissures: These are small tears in the lining of the anus, often caused by passing hard stools. They can lead to sharp pain during bowel movements and may result in fresh blood.

3. Gastrointestinal Conditions: Conditions such as diverticulosis, inflammatory bowel disease (IBD), or infections can lead to bleeding. Diverticulosis, for instance, involves the formation of small pouches in the colon wall that can bleed.

4. Dietary Factors: Sometimes, certain foods can irritate the gastrointestinal tract or cause changes in stool color. For example, beets can cause red stools, which may be mistaken for blood.

5. Medications: If you are taking any medications, especially blood thinners or non-steroidal anti-inflammatory drugs (NSAIDs), these can increase the risk of gastrointestinal bleeding.

6. Other Health Issues: Conditions affecting the upper gastrointestinal tract, such as peptic ulcers or esophageal varices, can also lead to blood in the stool, although this blood is typically darker due to the longer transit time through the digestive system.

Given your history of a clean colonoscopy and the recent onset of fresh blood in your stool, it is advisable to consult with your healthcare provider. They may recommend further evaluation, which could include a repeat colonoscopy, flexible sigmoidoscopy, or imaging studies to assess for other potential sources of bleeding.

In the meantime, monitor your symptoms closely. If you experience significant changes, such as increased bleeding, abdominal pain, or changes in bowel habits, seek medical attention promptly. It is crucial to address any new or concerning symptoms, especially when they involve rectal bleeding, to rule out serious conditions and ensure appropriate management.

In summary, while a clean colonoscopy is reassuring, fresh blood in the stool warrants further investigation to identify the underlying cause. Hemorrhoids, anal fissures, dietary factors, and other gastrointestinal conditions are all potential contributors that should be considered. Always consult with your healthcare provider for personalized advice and management based on your specific situation.

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